Sentences with phrase «types of cancer cells by»

It can also kill many different types of cancer cells by triggering apoptosis (programmed cell death) without affecting normal cells.

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Its drug Niraparib kills cancer cells by inhibiting the production of proteins called PARPs, which help repair damaged DNA strands, thereby hastening the death of some types of cancer cells.

Goji's are reported to have anti-aging properties and show anti-tumor activities against various types of skin cancer cells by inhibiting tumor growth and inducing apoptosis.

It is emerging that the chemical structure of RNA molecules is extensively modified by specific enzymes normally present in our cells, which are commonly found to be altered in severe medical syndromes and various types of cancers.

In the Cell study, Dr. Massagué, with Fellow Manuel Valiente, PhD, and other team members, found that in mouse models of breast and lung cancer — two tumor types that often spread to the brain — many cancer cells that enter the brain are killed by astrocytes.

The most common type of skin lymphoma is caused by the fact that specific immune cells — CD4 - T - lymphocyttes — turn into cancer cells.

Researchers at Penn State have combined the two approaches by taking biodegradable polymer nanoparticles encapsulated with cancer - fighting drugs and incorporating them into immune cells to create a smart, targeted system to attack cancers of specific types.

Now, by harnessing advances in genome editing to slice and dice genes in donor T cells, researchers have created a new type of cancer immunotherapy.

«For this reason, we decided to combine vitamin C with a PARP inhibitor, a drug type known to cause cancer cell death by blocking the repair of DNA damage, and already approved for treating certain patients with ovarian cancer.»

Qingdong Zheng, a materials scientist at John Hopkins University in Baltimore, Maryland, suggests that such biolasers could find uses in new types of sensors or in light - based therapeutics, in which light is used, for example, to kill cancer cells by triggering drugs into action that have already been administered.

A team led by professor Massimiliano Mazzone has demonstrated that the metabolism of macrophages, a particular type of white blood cell, can be attuned to prevent the spread of cancer.

Fragile skin that blisters easily: 90 percent of the patients that suffer from the skin condition recessive dystrophic epidermolysis bullosa (RDEB) develop rapidly progressing cutaneous squamous cell carcinomas, a type of skin cancer, by the age of 55.

Monoclonal antibodies are generated by clones of a type of white blood cell that have been fused to myeloma (cancer) cells to form fast - growing «hybridomas.»

Surprisingly, they found that although the patterns of gene expression — as shown by the RNA sequencing — differed between the hepatocellular carcinomas and the liver cancers with biliary phenotype and depended on the histological type, the overall pattern of mutations in the cells was actually similar between the tumors — of either type — that had emerged in patients who had had infections with either hepatitis C or B, and were different in patients without such infections.

«Although right now we are focusing on developing a cancer vaccine, in the future we could be able to manipulate which type of dendritic cells or other types of immune cells are recruited to the 3D scaffold by using different kinds of cytokines released from the MSRs,» said co-lead author Aileen Li, a graduate student pursuing her Ph.D. in bioengineering at Harvard SEAS.

Moffitt researchers wanted to determine if it would be possible to activate the cancer - fighting properties of T cells indirectly by targeting another type of immune cell called a dendritic cell.

Total remission, Alani said, may be possible with metronomic dosage, but the initial goal is not only to kill cancer cells but to create an environment in which it's very difficult for them to grow, largely by cutting off the large blood supply these types of cells often need.

Previous in vitro studies conducted by researchers in other countries showed that this molecule was able to reduce the multiplication and increase the mortality of cells from melanoma, the most aggressive type of skin cancer, as well as breast cancer and neuroblastoma, a tumor that typically affects patients aged 15 or younger.

Groundbreaking findings, published online in the journal journal Cancer Cell, show that resistance to many types of antibody drugs can be overcome by preventing cancer cells from «hiding» from immune Cancer Cell, show that resistance to many types of antibody drugs can be overcome by preventing cancer cells from «hiding» from immune cancer cells from «hiding» from immune cells.

This new combination approach prevents cancer cells from changing their diet (metabolically inflexible), and effectively starves them, by preventing them from using any other available types of bio-fuels.

He and colleagues from the University of Oregon, Reed College and Osaka University in Japan decided to look at actinomycin D, an antibiotic currently used to treat certain types of cancers by preventing cancer cells from transcribing, or copying, essential cancer information to new cells.

By seeding elements with an assortment of antibodies, the device could be set up to capture several different cancer cells types using a single blood sample.

Hsp90 inhibitors are among several innovative new types of treatment designed to attack cancer indirectly, by destabilising multiple different proteins required for the growth and survival of cancer cells.

A higher intake by postmenopausal women of the natural antioxidant lycopene, found in foods like tomatoes, watermelon and papaya, may lower the risk of renal cell carcinoma, a type of kidney cancer.

Scientists have known that LPA is secreted by many types of cancer cells, appears to promote the growth and spread of tumor cells, and that immune cells known as CD - 8 «killer» T cells have several receptors for LPA.

«Since MCR works by targeting specific DNA sequences, in cases where diseased cells have altered DNA as in HIV - infected individuals or some types of cancer, MCR - based methods should be able to distinguish diseased from healthy cells and then be used to selectively either destroy or modify the diseased cells.»

A research team, led by Chao Cheng, Ph.D., Assistant Professor in the Department of Genetics at The Geisel School of Medicine at Dartmouth, used gene expression data from breast cancer patients to computationally infer the presence of different types of immune cells.

Acute myeloid leukemia (AML) is characterized by a rapidly - developing cancer in the myeloid line of blood cells, which is responsible for producing red blood cells, platelets and several types of white blood cells called granulocytes.

An anti-PD-1 antibody developed by Bristol - Myers Squibb generates excitement with results from a phase I trial showing that, among 236 patients with various types of cancer, the treatment shrank tumors in 28 percent of melanoma patients, 30 percent of patients with kidney cancer, and 18 percent of patients with advanced non-small cell lung cancer.

This subgroup of AML is trickier than APL, where the product of the gene created by the chromosomal rearrangement directly blocks the cancer cells from becoming their normal type.

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The study relates to a particular type of vaccine (killed) against a particular virus, influenza, though the findings might hold true for other killed vaccines and for those vaccines consisting only of proteins produced by GM in bacteria, yeast or insect cells, against diseases such as hepatitis B (HBV) and human papilloma virus (HPV, the causative agent of cervical cancer).

NHL represents a diverse group of diseases distinguished by the characteristics of the cancer cells associated with each disease type.

Home > Specialties > Cancer Care > Information by Type of Cancer > Blood and Bone Marrow Stem Cell Transplantation >

The knowledge about how this cancer form arises and develops is still limited but new results from a research team led by Lene Uhrbom, Uppsala University / SciLifeLab, shows that disease progress and the malignancy are affected by the cell type from which the tumor originates as well as the age of the patient.

There are several types of brain cancer, classified by the type of cell from which they originate.

Leukemia is a cancer of the bone marrow and blood and is classified by cell type and rate of growth: acute lymphocytic, chronic lymphocytic, acute myeloid, and chronic myeloid.

In 1993, while at the Sloan - Kettering Cancer Center in New York, Rothman performed the key experiment that has forever linked his work to that of Thomas Südhof and Richard Scheller, by demonstrating that the same molecules that control this process in the nervous system, in the release of signaling molecules called neurotransmitters, are important to vesicle transport and fusion in all cell types.

Weaver also said that the predictions made by jamming models resemble what biologists call extrusion, a process by which dead epithelial cells are squeezed out of crowded tissue — the disfunction of which has recently been implicated in certain types of cancer.

Cancer can develop not just because of changes in the types and amounts of proteins present in a cell but also due to changes in how those proteins are modified — for example, by attachment of sugars (glycosylation).

To develop the methodology, the group analyzed the molecular profiles of human embryonic stem cells and compared them with data for 12,000 samples of 33 different tumor types held by The Cancer Genome Atlas (TCGA), a U.S. public database.

In cancer, Tregs are recruited by tumors and prevent other types of T cells, including cytotoxic T cells (also called CD8 cells) from attacking and destroying cancer cells.

Important features of XMRV biology include (1) tropism for a variety of cell lines, including prostate cancer DU145 and LNCaP cells [27], [43], [48], and human neural cell types [57], (2) adaptations that promote growth in prostate epithelium and human - derived prostate cancer cell lines including an androgen response element in the promoter region [58] and downregulation of APOBEC3G [59], and (3) cellular effects with potential oncogenic properties including increased tumor aggressiveness mediated by downregulation of p27 [60] and differential regulation of several microRNAs [61].

Neutrophils, the most common type of white blood cell, can be taken over by cancer cells and used as an aid in metastasis...

that specifically inhibit tumor growth by targeting the Hedgehog pathway have been approved by the FDA to treat basal cell carcinoma, giving patients with advanced cases of this type of skin cancer a better chance of survival.

Since 2012, two drugs that specifically inhibit tumor growth by targeting the Hedgehog pathway have been approved by the FDA to treat basal cell carcinoma, giving patients with advanced cases of this type of skin cancer a better chance of survival.

Of note, certain types of cancer cell, including pancreatic and lung cancer cells, are heavily reliant on growth benefits brought by autophagy activation, therefore becoming «addicted» to autophagOf note, certain types of cancer cell, including pancreatic and lung cancer cells, are heavily reliant on growth benefits brought by autophagy activation, therefore becoming «addicted» to autophagof cancer cell, including pancreatic and lung cancer cells, are heavily reliant on growth benefits brought by autophagy activation, therefore becoming «addicted» to autophagy.

The final stage is headed by Jian Jin, a member of the UNC Lineberger Comprehensive Cancer Center, will develop new compounds that will allow researchers to even more precisely activate the G - coupled receptors of individual cell types in the particular brain regions.

It's prescribed to treat a type of skin cancer called superficial basal cell carcinoma, and precancerous skin lesions caused by sun exposure, called actinic keratosis.

IL - 15 is typically used by the body to trigger the production of Natural Killer (NK) immune cells - a type of white blood cell used in fighting cancer and infection.