Not exact matches
• Zealand Pharma, a Denmark - based biotech focused on peptide - based
medicines for
type 2
diabetes, has filed for an IPO
of American Depository Shares.
They can happen to anyone, but they occur more often in older people, obese people, and those with
type 2
diabetes, and they tend to crop up where skin rubs against skin, like the armpits, groin, and folds
of the neck, according to the US National Library
of Medicine (NLM).
The June 14, 2010 issue
of the Archives
of Internal
Medicine contains the results
of a Harvard study which shows that five or more servings
of white rice per week increases your risk
of developing
type 2
diabetes, but two servings
of brown rice per week decreases your risk.
«Population studies have consistently supported a protective role
of nuts against cardiometabolic disorders such as cardiovascular disease and
type 2
diabetes, and we know that inflammation is a key process in the development
of these diseases,» said corresponding author Ying Bao, MD, ScD, an epidemiologist in BWH's Channing Division
of Network
Medicine.
Researchers at the University
of Maryland School
of Medicine have identified a mutation in a fat - storage gene that appears to increase the risk for
type 2
diabetes and other metabolic disorders, according to a study published online in the New England Journal
of Medicine.
«We found that Amish people with this mutation have defects in fat storage, increased fat in the liver, high triglycerides, low «good» (HDL) cholesterol, insulin resistance and increased risk
of developing
type 2
diabetes,» says the study's senior author, Coleen M. Damcott, Ph.D., an assistant professor of medicine in the Division of Endocrinology, Diabetes and Nutrition and member of the Program for Personalized and Genomic Medicine at the University of Maryland School of M
diabetes,» says the study's senior author, Coleen M. Damcott, Ph.D., an assistant professor
of medicine in the Division of Endocrinology, Diabetes and Nutrition and member of the Program for Personalized and Genomic Medicine at the University of Maryland School of M
medicine in the Division
of Endocrinology,
Diabetes and Nutrition and member of the Program for Personalized and Genomic Medicine at the University of Maryland School of M
Diabetes and Nutrition and member
of the Program for Personalized and Genomic
Medicine at the University of Maryland School of M
Medicine at the University
of Maryland School
of MedicineMedicine.
In some 3000 elderly people, Nir Barzilai
of the Albert Einstein School
of Medicine in the Bronx, New York, and his colleagues plan to conduct a trial in which half the subjects would get a placebo and half would get an old (indeed, ancient) drug for
type 2
diabetes called metformin, which has been shown to modify aging in some animal studies.
A link between
diabetes and statins wasn't discovered until a 2008 analysis
of almost 18,000 people published in the New England Journal
of Medicine, which found that 216 people taking a placebo developed
type 2
diabetes while 270 taking a statin did.
Probing the link between adiponectin deficiency and metabolic disorders like
diabetes and obesity, researchers from the Albert Einstein College
of Medicine in New York City injected adiponectin into wild -
type mice, diabetic mice, and obese diabetic mice.
«Scientists are starting to appreciate the importance
of beta cells in understanding why
type 1
diabetes occurs,» says Soleimanpour, a U-M assistant professor
of medicine.
Writing in the Sept. 23 online edition
of the journal
Diabetes Care, the authors — including UNC's John Buse, MD, PhD, professor of medicine and director of the UNC Diabetes Care Center — say that patients who have a fasting blood sugar of 126 or higher are diagnosed with type 2 diabetes, and most patients are prescribed the first line medication me
Diabetes Care, the authors — including UNC's John Buse, MD, PhD, professor
of medicine and director
of the UNC
Diabetes Care Center — say that patients who have a fasting blood sugar of 126 or higher are diagnosed with type 2 diabetes, and most patients are prescribed the first line medication me
Diabetes Care Center — say that patients who have a fasting blood sugar
of 126 or higher are diagnosed with
type 2
diabetes, and most patients are prescribed the first line medication me
diabetes, and most patients are prescribed the first line medication metformin.
A new study by researchers from the University
of Chicago
Medicine, based on a 6 - month clinical trial, finds that use
of a CGM is cost - effective for adult patients with
type 1
diabetes when compared to daily use
of test strips.
«If you, by chance, inherit the risk version
of this gene from your mother, then you're at higher risk for
type 2
diabetes,» explained researcher Mete Civelek, PhD,
of the University
of Virginia School
of Medicine.
An inexpensive, portable, microchip - based test for diagnosing
type - 1
diabetes could improve patient care worldwide and help researchers better understand the disease, according to the device's inventors at the Stanford University School
of Medicine.
Researchers led by Dr. Sirimon Reutrakul, associate professor
of endocrinology,
diabetes and metabolism in the University
of Illinois at Chicago College
of Medicine, wanted to determine if morning or evening preference among people with
Type 2
diabetes was associated with an increased risk for higher BMI and if so, what specific factors about evening preference contributed to the increased risk.
«A strategy to protect the remaining amounts
of insulin produced by diabetics in response to blood sugar levels is an attractive treatment alternative, particularly in the early stages
of type II
diabetes,» said Dr. Seeliger, Assistant Professor in the Department
of Pharmacological Sciences at Stony Brook University School
of Medicine.
«We see a dose - response relationship between frequency
of night shift work and
type 2
diabetes, where the more often people do shift work, the greater their likelihood
of having the disease, regardless
of genetic predisposition,» said co-first author Céline Vetter, PhD who conducted this work while at the Channing Division
of Network
Medicine at BWH, along with co-first author Hassan S. Dashti, PhD, RD. Vetter is now an assistant professor at the University
of Colorado, Boulder.
«Our results suggest that these two risk factors both play a role in
type 2
diabetes likelihood,» said corresponding co-senior author Frank A.J.L. Scheer, PhD, Director
of the Medical Chronobiology Program and neuroscientist in the Division
of Sleep and Circadian Disorders in the Departments
of Medicine and Neurology at BWH.
Researchers at University
of California San Diego School
of Medicine, with colleagues at the National Institute
of Diabetes and Digestive and Kidney Diseases, the University of Manitoba and St. Boniface Hospital Albrechtsen Research Centre in Canada, have identified a molecular signaling pathway that, when blocked, promotes sensory neuron growth and prevents or reverses peripheral neuropathy in cell and rodent models of type 1 and 2 diabetes, chemotherapy - induced neuropathy
Diabetes and Digestive and Kidney Diseases, the University
of Manitoba and St. Boniface Hospital Albrechtsen Research Centre in Canada, have identified a molecular signaling pathway that, when blocked, promotes sensory neuron growth and prevents or reverses peripheral neuropathy in cell and rodent models
of type 1 and 2
diabetes, chemotherapy - induced neuropathy
diabetes, chemotherapy - induced neuropathy and HIV.
«These findings are important because depression is common in patients with
type 2
diabetes,» said lead investigator Sirimon Reutrakul, M.D., an associate professor at Mahidol University Faculty
of Medicine, Bangkok, Thailand.
When the deformed pancreas proteins were injected into mice without
type 2
diabetes, the animals developed symptoms
of the disease, including overly high blood sugar levels, the researchers report online August 1 in the Journal
of Experimental
Medicine.
«The data are impressive and may have opened a new field
of investigation in metabolic function and
type 2
diabetes,» said Dr. Samuel Klein, chief of the Division of Geriatrics and Nutritional Science at the Washington University School of Medicine Diabetes Research
diabetes,» said Dr. Samuel Klein, chief
of the Division
of Geriatrics and Nutritional Science at the Washington University School
of Medicine Diabetes Research
Diabetes Research Center.
In 2002, the research team for TRIGR (Trial to Reduce IDDM in the Genetically at Risk), led in the U.S. by principal investigator Dorothy Becker, M.D., professor
of pediatrics at Children's Hospital and the University
of Pittsburgh School
of Medicine, embarked on a large - scale study
of 2,159 infants with a family member affected by
type 1
diabetes and with genetic risk for
type 1
diabetes to find out whether delaying the exposure to complex foreign proteins such as cow's milk proteins would decrease the risk
of diabetes.
«We have walkable neighbourhoods in many towns and cities in Canada, but they have to actually be used to help us reduce our risks
of developing chronic conditions like
type 2
diabetes and its associated complications,» says study senior author, Dr. Kaberi Dasgupta, MUHC internal
medicine physician and an associate professor
of medicine at McGill University.
In the lifestyle modification group, however, even individuals with two copies
of the variant were no more likely to develop
type 2
diabetes than participants without the variant, the team reports 20 July in the New England Journal
of Medicine.
Professor Melanie Davies, Director
of the NIHR Leicester Biomedical Research Centre, UK, Professor
of Diabetes Medicine at the University of Leicester and a co-author of the study, said: «Lack of physical activity and being overweight are two risk factors associated with type 2 d
Diabetes Medicine at the University
of Leicester and a co-author
of the study, said: «Lack
of physical activity and being overweight are two risk factors associated with
type 2
diabetesdiabetes.
In 2010 two US pharmaceutical companies created a variant
of an R - ATA allowing industrial - scale synthesis
of sitagliptin, a
medicine for
type - 2
diabetes.
The finding builds on an earlier surprise from the Joslin Medalist Study program, which looks for clues on how some people live with
type 1
diabetes for more than 50 years with unusually low levels
of complications, says George King, M.D., Joslin's Chief Scientific Officer and Professor
of Medicine at Harvard Medical School.
Now, however, a team
of researchers led by Yu - Hua Tseng, Ph.D., Investigator in the Section on Integrative Physiology and Metabolism at Joslin
Diabetes Center and an Associate Professor
of Medicine at Harvard Medical School, has created cell lines
of human brown and white fat precursor cells that will help investigators to pick apart the factors that drive the development and activity
of each
type of cell.
The research spanned 10 years and its efficacy was shown in mice and in 20
type 1
diabetes patients who took part in a clinical trial at the Barbara Davis Center for Childhood Diabetes at the University of Colorado School of M
diabetes patients who took part in a clinical trial at the Barbara Davis Center for Childhood
Diabetes at the University of Colorado School of M
Diabetes at the University
of Colorado School
of Medicine.
The scientists became interested in studying salsalate, an anti-inflammatory drug, after research conducted by Steven Shoelson, M.D., Ph.D., Head
of the Section on Pathophysiology and Molecular Pharmacology and Professor
of Medicine at Harvard Medical School, identified inflammation as a factor in the development
of type 2
diabetes.
«The problem arises from autoimmunity, a condition that people with
type 1
diabetes already have,» says Myra A. Lipes, M.D, investigator in the Section on Immunology at Joslin and principal investigator
of a study published in the June 13 edition
of the journal Science Translational
Medicine.
«This is one
of the very first studies
of human iPSC models for
type 2
diabetes, and it points out the power
of this technology to look at the nature
of diabetes, which is complex and may be different in different individuals,» says C. Ronald Kahn, MD, Joslin's Chief Academic Officer and the Mary K. Iacocca Professor
of Medicine at Harvard Medical School.
Widely used treatments for
type 2
diabetes have different effects on the hearts
of men and women, even as the drugs control blood sugar equally well in both sexes, according to researchers at the School
of Medicine.
«This is the first personalized treatment for
type 1
diabetes prevention,» said Aaron Michels, MD, a researcher at the Barbara Davis Center for Childhood Diabetes and associate professor of medicine at CU A
diabetes prevention,» said Aaron Michels, MD, a researcher at the Barbara Davis Center for Childhood
Diabetes and associate professor of medicine at CU A
Diabetes and associate professor
of medicine at CU Anschutz.
Characteristics
of the gut microbiota in adult patients with
type 1 and 2
diabetes based on the analysis
of a fragment
of 16S rRNA gene using next - generation sequencing — Dominika Salamon — Polish Archives
of Internal
Medicine
Sparked from the efforts
of the T2D - GENES Consortium (
Type 2
Diabetes Genetic Exploration by Next - generation sequencing in multi-Ethnic Samples; T2D - GENES) to aggregate and share results from large - scale T2D sequence and genotype datasets, the prototype T2D KP was built with seed funding from the NIDDK via the T2D - GENES Consortium and the Slim Initiative for Genomic
Medicine in the Americas for T2D (SIGMA T2D).
Improving Adherence In
Type 2
Diabetes By Communication Training: Evaluation
of a CME Initiative Mila Kostic Director, Continuing Medical Education, The Perelman School
of Medicine at the University
of Pennsylvania, Suzanne Murray President & Founder, AXDEV Group, Maja Drenovac, PharmD Associate Director, Educational Programs, Vemco MedEd, Originally presented at the Global Alliance for Medical Education Annual Meeting, Munich, Germany, June 2011
This thinking has resulted in an entire catalogue
of hundreds
of research studies that has shed light on the genetic origins
of diseases such as
type 2
diabetes, Parkinson's disease, Crohn's disease, and prostate cancer, while helping fuel the rise
of personalized
medicine.
11/6/2007 UCSD Researchers Discover Inflammation, Not Obesity, Cause
of Insulin Resistance Findings may have important potential for new drug discoveries in fight against
Type 2
diabetes Researchers at the University
of California, San Diego (UCSD) School
of Medicine have discovered that inflammation provoked by immune cells called macrop... More...
Angela C Estampador, 1,2 Paul W Franks1, 3,4 1Department
of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Skåne University Hospital Malmö, Malmö, Sweden; 2Department
of Endocrinology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark; 3Department
of Public Health and Clinical
Medicine, Umeå University, Umeå, Sweden; 4Department
of Nutrition, Harvard School
of Public Health, Boston, MA, USA Abstract: Evidence has emerged across the past few decades that the lifetime risk
of developing morbidities like
type 2
diabetes, obesity, and cardiovascular disease may be influenced by exposures that occur in utero and in childhood.
While women who are pregnant, breastfeeding or may become pregnant are often excluded from clinical trials for
type 2
diabetes drugs, the exclusion is not based on the risk
of fetal harm, according to Penn State College
of Medicine researchers.
March 25, 2015 New analysis finds successes, gaps in community - based
diabetes prevention programs Lifestyle interventions designed to reduce the risk
of developing
type 2
diabetes can work well in group - based, community settings, conclude authors from the University
of Chicago
Medicine in a new report issued by the New York State Health Foundation (NYSHealth) on March 25, 2015.
Others need oral
medicines, insulin, other injectable medications, or some combination
of type 2
diabetes med — along with healthy food and fitness — to keep blood sugar in check.
Despite this, many integrative and functional
medicine doctors have been suggesting a low - carb diet plan for
diabetes for years,, and many people — including the parents
of type 1 diabetics — have had amazing success with low - carb nutrition plans.
A study in the Annals
of Internal
Medicine found that obese patients with
type - 2
diabetes who went keto for just two weeks improved insulin sensitivity by 75 %.
It's not surprising that Ayurvedic
medicine favoured cinnamon for treating
type 2
diabetes for hundreds
of years.
«Plant - Based Dietary Patterns and Incidence
of Type 2
Diabetes in US Men and Women: Results from Three Prospective Cohort Studies,» Ambika Satija, Shilpa N. Bhupathiraju, Eric B. Rimm, Donna Spiegelman, Stephanie E. Chiuve, Lea Borgi, Walter C. Willett, JoAnn E. Manson, Qi Sun, Frank B. Hu, PLOS
Medicine, online June 14, 2016, doi: 10.1371 / journal.pmed.1002039.
In 2005, in the Annals
of Internal
Medicine, the article «Effect
of a Low - Carbohydrate Diet on Appetite, Blood Glucose Levels, and Insulin Resistance in Obese Patients with
Type 2
Diabetes» showed that 2 weeks
of a very low carbohydrate diet with no caloric restrictions reduced appetite and body weight.
By applying the principles
of Functional
Medicine we see people reverse disease — autoimmune disease,
type 2
diabetes, digestive disorders, allergies, migraines, mood disorders, chronic fatigue and much more.