Using animal models of precancerous polyps in the bowel, Chung and his team determined that certain
types of immune cells within a chronically inflamed intestine can become rewired, causing them — paradoxically — to contribute to disease development rather than protect against it.
Not exact matches
It is the stuff
of dreams for flu scientists, but it could be
within reach if a new
type of vaccine that elicits an
immune response from white blood
cells is combined with traditional vaccines.
Current thinking regarding
type III hypersensitivity is that
immune cells within tissues sense the presence
of these
immune complexes (ICs) through specific receptor molecules and release inflammatory factors called cytokines that activate the endothelial
cells lining adjacent blood vessels to promote the recruitment
of neutrophils.
Once lymphocytes find such invaders
within the lymph node, they destroy them in collaboration with other
types of immune cells.
And this in spite
of the fact that all the various
types of blood
cells within a lymph node, including the
immune cells, are constantly replaced, which means the lymph nodes» location memory must be encoded somewhere in its stroma.
The bacteria hide
within human
cells called macrophages, escaping the body's own
immune defenses and being shielded from many
types of antibiotics.
Type, density, and location
of immune cells within human colorectal tumors predict clinical outcome.
But novel genomic tools are beginning to reveal new, rare
cell types as well as unexpected variability and plasticity
within groups upending the traditional view
of immune cells assigned to the same category as unvarying entities that behave in a constant manner.
For decades, scientists have been seeking a new
type of vaccine that activates another player in the
immune system called a T
cell to fight off infections
within different organs.
The idea: trigger
immune activity
within the brain itself to kill remaining tumor
cells — the ones neurosurgeons can't take out, which make this
type of tumor so dangerous.