«These highly elusive 3 - nanometer structures are too small to be captured with other
types of liquid biopsy devices, such as microfluidics, due to shear forces that can potentially destroy them,» he noted.
Bramlett explains that manufacturers initially focused on providing large panels of control samples to cover as many
types of liquid biopsy experiments as possible.
«In the long - term, there is the possibility that
this type of liquid biopsy method could be used for screening,» he said.
Not exact matches
We're also making progress on our
liquid biopsy program since our last update, including the recently announced collaboration with Memorial Sloan Kettering Cancer Center, which is focused on furthering the basic understanding
of the biology
of circulating tumor DNA, or ctDNA, in different cancer
types.
«The problem with plasma cell - free
liquid biopsy in particular is that the amount
of wild -
type [DNA] can be very, very high, and so keeping that really rare signal from being swamped out by the wild -
type... is key,» says Dawne Shelton, R&D manager for in vitro diagnostic products at Bio-Rad in Hercules, California.
The research ideas you develop at the workshop should: • Lead to the significant advancement
of our understanding
of sensor technologies suitable for
liquid biopsy • Consider the practical challenges
of low volume
liquid usually taken for analysis and the inconsistency
of sample preparation across point
of care sites • Prioritise biomarkers with high specificity for cancer or even for multiple cancer
types, including markers specific to cancers that will become aggressive as opposed to non-lethal disease
«
Liquid biopsy is one
of the most promising tools emerging for the management
of cancer,» said Kelley «and we are excited about the potential
of our technology to streamline this
type of testing.»