Comparing the two
types of mutations allowed the team to spot genes that have had changes favoured by natural selection while taking into account the background mutation rate.
Not exact matches
Scientists are beginning to identify cancer by its
mutations rather than just its tissue
of origin,
allowing them to find drugs more precisely targeted to a particular disease
type.
By solving the origins and the reassortments that led to the 2009 A / H1N1 pandemic, researchers might be able to study existing «brothers and sisters»
of the virus to understand the
type of mutations needed to
allow a virus to jump into humans.
The
types of tumor that can be particularly responsive to immunotherapy generally happen in older people, or people who have genetic factors that
allow their tumors to acquire a lot
of mutations — so that the tumor has a lot
of different antigens that are recognized by the immunotherapy.
We developed SomaticSniper to detect somatic
mutations in whole - genome sequencing data while
allowing for tumor contamination
of normal cells that occurs in some
types of leukemia.
By replacing a relatively large region
of DNA, the technique
allows the scientists to fix many gene
mutations at once, which suggests the method might provide a way to treat hundreds
of types of HBB - related diseases.
This provided the mechanism by which bacteria acquire immunity to specific viral infections,
allowed introduction
of specific
mutations at desired sites, and provided the means to transfer efficient Cas9 - directed break, repair, and editing to any cell
type.
Dogs affected with
Type I vWD have a
mutation which
allows normal vWF to be produced part
of the time, so even dogs with two copies
of the defective gene (affected dogs) have some minimal amount
of normal vWF.
Many
types of phytoplankton do increase their numbers rapidly but they propagate primarily by asexual reproduction, which makes it less likely for populations to accumulate the genetic
mutations that could
allow them to adapt.