Not exact matches
«The interaction between the two
types of neurons could also help explain the presence
of seizures in patients with schizophrenia, dementia and some
forms of autism.»
«Our work suggests that the neural pathology
of autism manifests in the earliest cortical circuits,
formed by a cell
type called subplate
neurons,» said UMD Biology Professor and senior study author Patrick Kanold.
LPA receptors are all over neural progenitor cells, which go on to
form neurons and other
types of cells in a young brain.
In an experimental setup that allowed the two
types of cells to bathe in the same fluid without coming into physical contact, retinal
neurons in a bath with hUTCs
formed new connections between
neurons called synapses, and they sprouted new «neurites» — tiny branches that lead to additional connections.
All
formed the same
types of stem cells, which give rise to «progenitor» cells that, in turn, divide into
neurons and eventually organize themselves in six layers
of brain tissue.
The research also answers a long - standing question about why motor
neurons, the nerve cells
of the spinal cord that control muscle movement,
form much faster than other
types of neurons.
In vertebrates, the axons
of many
neurons are sheathed in myelin, which is
formed by either
of two
types of glial cells: Schwann cells ensheathing peripheral
neurons and oligodendrocytes insulating those
of the central nervous system.
Neurobiologist Marta Florio and her team made the discovery while studying a
type of neural stem cell that
forms neurons when embryos develop.
«Now that we have the cellular and molecular information, the future promises to be very exciting when this knowledge can be used to understand how this system is
formed during gestation and how the different
neuron types go about controlling the body's functions,» says study leader Patrik Ernfors, professor
of tissue biology
In studies
of neural development in mice, Stahl found that TRNP1 produces a protein that determines whether neural stem cells self - replicate, leading to a balloonlike expansion
of cortical surface area, or whether they differentiate into a plethora
of intermediate stem cell
types and
neurons, thickening the cortex and
forming more complex brain structures.
The most severe
form of SMA is
Type 1, a lethal genetic disorder characterized by motor
neuron loss and associated muscle deterioration, which results in mortality or the need for permanent ventilation support before the age
of two for greater than 90 percent
of patients.
Scientists recently announced that blood stem cells, a
type of adult stem cell,
form cells that look suspiciously like
neurons — brain cells.