The eyes contain two different
types of photoreceptor cells that affect the way everyone sees things, and this is true of both dogs and people.
It took nearly eight decades for scientists to investigate his claim and prove him right: The eye really does contain a third
type of photoreceptor cells that sense light intensity without detecting images.
Not exact matches
The downside is that people with these eye diseases are losing sight in large part because they're losing a different
type of eye
cell: the
photoreceptors that sense light in the retina.
After initiating
photoreceptor loss in the fish retinas, the researchers monitored the immune system's response by tracking the activity
of three
types of fluorescently labeled immune
cells in and around the eye: neutrophils, microglia and peripheral macrophages.
They were able to follow the activity
of the immune
cells using time - lapse 3 - D microscopy imaging
of fish retinas and found that neutrophils, the
type of immune
cells that are typically the first responders to tissue injury, were largely unresponsive to
photoreceptor death.
The second layer is made
of bipolar
cells that act as a conduit between the
photoreceptor and the third
type of cell, the ganglion, which transmits the light signals to the brain.
Functional damage to these
photoreceptors, or pathological loss
of the
cells that bear them, results in inability to register light impinging on the retina — and is responsible for various
types of visual impairment and certain forms
of congenital blindness.
The researchers injured the mice retinas with a toxin that causes
cell death in retinal ganglion
cells and interneurons, another
type of retinal
cell whose job it is to transmit signals from
photoreceptors to the brain.
In wild -
type, retinal ganglion
cell layer (GCL), inner nuclear layer (INL), inner plexiform layer (IPL), and nuclear layers
of rod and cone
photoreceptors are distinct, and rod outer segment (OS) is observed at the outer-most layer
of the retina.
These
cells can develop into any
type of retinal
cell, including RPE
cells or
photoreceptors.
These retinal
cells are the
type that are killed off in macular degeneration, eventually leading to the death
of photoreceptors, and the gradual loss
of central vision.