Sentences with phrase «types of stem cells in»

They also believe that SIRT1 might be important to maintaining the health of other types of stem cells in the body, which may be linked to overall aging.

Not exact matches

However, embryonic stem cells remain the «gold standard,» and studies of all types of stem cells should continue in parallel for the foreseeable future.»

It's blood in a newborn baby's umbilical cord that's rich in a type of stem cell called hematopoietic progenitor cells (HPCs).

The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.

In addition to maintaining stem cell populations and keeping the brain supplied with all its cell types, the investigators showed that NAD also is vital for the process of cognition itself.

Furthermore, by making use of embryonic stem cells and in vitro differentiation, SIF - seq can be used to assess enhancer activity in a wide variety of disease - relevant cell types.»

To develop their «disease in a dish» model, the team took skin cells from patients with Allan - Herndon - Dudley syndrome and reprogrammed them into induced pluripotent stem cells, which then can be developed into any type of tissue in the body.

A new type of human stem cell, never seen in nature, should be better at making replacement organs than existing stem cells

These cells, which can become several different types of blood cells, are similar to the specialized stem cells found in bone marrow that can churn out new blood cells.

Because they can differentiate into almost any cell type in the body, stem cells have the potential to be used to create healthy cells to treat a number of diseases.

Trials of cells made from human embryonic stem cells are also poised to begin in people with type 1 diabetes and heart failure, the first time embryonic stem cells have been used in the treatment of major lethal diseases.

«We've shown that SIF - seq can be used to identify enhancers active in cardiomyocytes, neural progenitor cells, and embryonic stem cells, and we think that it has the potential to be expanded for use in a much wider variety of cell types,» Dickel says.

We wanted to understand what types of differences are always there, what is causing them, and what they mean,» says Juan Carlos Izpisua Belmonte, a professor in Salk's Gene Expression Laboratory and co-senior author, with Kelly Frazer of the University of California, San Diego, on the new paper, which was published in Cell Stem Cell in April 2017.

Further ahead, he is looking to an emerging technology known as induced pluripotent stem cells (iPSCs), in which adult cells are reprogrammed to be like embryonic stem cells so they can transform into any type of cell.

TWO types of human ear cell have been grown in the lab from fetal stem cells.

Hematopoietic stem cells, that form mature blood cells, require a very precise amount of protein to function — and defective regulation of protein production is common in certain types of aggressive human blood cancers.

The project's goals were to explore and describe the range of epigenetic changes that take place in bone marrow as stem cells develop into different types of mature blood cell.

In past projects, scientists have tried to derive various types of differentiated cells from stem cells — such as bone, tissue, nerves or fat — directly from hiPSCs.

Slight modifications in their genome sequences play a crucial role in the conversion of pluripotent stem cells into various differentiated cell types.

As the heart starts pumping a primitive blood - like fluid around the body of an embryo, the change in pressure from the flowing liquid is the cue for cells lining the aorta to change first into blood stem cells, then into all blood - cell types in the body.

Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

The molecules — called SMAD2 and SMAD3 — can enhance the efficiency of converting mature cells into induced pluripotent stem cells, which have the distinctive ability to become any type of cell found in the body.

Bone marrow transplants are sometimes needed to treat immune diseases that attack these stem cells, or in certain types of anaemia, in which the body can't make enough blood cells or clotting factors.

«We have found a unique group of cells that bring together the essential qualities of both types of stem cells for the first time,» says Colin McGuckin of Kingston University in Surrey, UK, who co-led the team with colleague Nico Forraz.

«Just as normal cells with the same genome differentiate into many different cell types, a single tumor characterized by specific genetic mutations can contain many different types of cells — stem - like and more differentiated cells — with the difference being rooted in their epigenetic information.

This type of stem cell, called an oligodendrocyte progenitor cell, is found in the brain and spinal cord.

«Maybe the invention of this new type of stem cell was important in driving brain evolution,» says Mueller.

The two - part approach netted a set of mutations seen only at relapse that enabled the team to sift and sort leukemic and normal stem cells using tools developed in the Dick lab a few years ago to zero in on specific cell types fated to relapse.

It was thought that different layers of neurons are generated in successive waves by a single type of stem cell.

The back - and - forth attachment and removal of methyl groups also fine - tunes gene expression in stem cells, which can mature, specialize and multiply to become muscle, bone, nerve, or other cell types.

ERRORS have occurred in a type of stem cell that could be used instead of embryonic stem cells — and in tissues made from them.

The first hESC was isolated in 1998, and researchers are still working to find the strengths and nuances of each type of stem cell.

«Disturbances to these processes may cause neuronal stem cells to develop into different types of cells or may cause neurons to migrate to different locations in the brain, changing neuronal circuitry and potentially leading to behavioral disorders like schizophrenia.»

The therapeutic use of stem cells is a promising area of medicine for the decades ahead and researchers are examining why stem cells function in certain types of niches, microenvironments, and pockets of activity.

The Karlssons were referred to the Karolinska University Hospital in Stockholm, where physicians proposed a radical strategy: Harvest a specific type of stem cell from the liver of an aborted fetus and infuse it through the umbilical vein into the fetus that Madeleine was carrying.

First produced only in the past decade, human induced pluripotent stem cells (iPSCs) are capable of developing into many or even all human cell types.

By tinkering with the medium in which cells are grown, researchers at the Salk Institute for Biological Studies created a type of stem cell with a survival rate of 30 to 40 percent, vs. 1 percent.

Now, with new kinds of technologies that are coming up, new types of tissue engineering and, you know, some of the hopes that people have for stem cells and [the] like, it may be interesting to see if there are other ways, alternatives to dealing with really badly damaged hearts that would involve growing a new heart or replacing or repairing the damage d to a badly damaged heart that might make artificial hearts less important in the somewhat more distant future.

By turning on a several genes in adult cells, scientists can transform skin or blood cells into stem cells that can become every cell type in the body — without the ethical and practical complications of using embryos or oocytes.

Human epidermal equivalents representing different types of skin could also be grown, depending on the source of the stem cells used, and could thus be tailored to study a range of skin conditions and sensitivities in different populations.»

Semenza says methylation leads to the destruction of NANOG's mRNA so that no protein is made, which in turn causes the embryonic stem cells to abandon their stem cell state and mature into different cell types.

The company's goal is to create a comprehensive source of stem cells that could be of particular use for treating people of Middle Eastern descent, whose tissue types are often underrepresented in the public tissue banks such as those in the U.S. and elsewhere.

Looking further into the intestinal crypts of both the transgenic and wild - type mice, the research team made what they consider a surprising finding: Not only was HMGA1 causing the stem cells themselves to self - renew or proliferate more rapidly in the transgenic animals, but it was also increasing the number of Paneth cells, a type of niche cell known to support intestinal stem cells.

In a second study, they applied CellNet's teachings to a recurring question in stem cell biology: Is it feasible to directly convert one specialized cell type to another, bypassing the laborious process of first creating an iPS celIn a second study, they applied CellNet's teachings to a recurring question in stem cell biology: Is it feasible to directly convert one specialized cell type to another, bypassing the laborious process of first creating an iPS celin stem cell biology: Is it feasible to directly convert one specialized cell type to another, bypassing the laborious process of first creating an iPS cell?

What he instead plans to do is turn the iPSCs into blood - forming stem cells, which when transplanted into the body would give rise to all of the cell types found in the blood.

«Research shows a cause of gastrointestinal symptoms in Type 1 diabetes: Excess of growth factor binding protein damages colon - maintaining stem cells.»

Using next - generation sequencing technologies that were previously unavailable, Michael Gardner, a graduate research assistant, and Jianying Wang, a senior research associate in Mitchum's lab, made a remarkable new discovery — nematodes possess the ability to produce a second type of peptide that can effectively «take over» plant stem cells that are used to create vital pathways for the delivery of nutrients throughout the plant.

Now a UC Santa Barbara researcher has added to that body of knowledge by determining how stem cells produce different types of «daughter» cells in Drosophila (fruit flies).

In Arabidopsis, as in most plants, there is a specific zone near the tip of the root where stem cells transition from a stage of proliferation to one where they differentiate into specific tissue typeIn Arabidopsis, as in most plants, there is a specific zone near the tip of the root where stem cells transition from a stage of proliferation to one where they differentiate into specific tissue typein most plants, there is a specific zone near the tip of the root where stem cells transition from a stage of proliferation to one where they differentiate into specific tissue types.

One of the reasons pluripotent stem cells are so popular in medical research is that they can be differentiated into any cell type.