Sentences with phrase «types of tissue as»

Not exact matches

In past projects, scientists have tried to derive various types of differentiated cells from stem cells — such as bone, tissue, nerves or fat — directly from hiPSCs.

Action potentials can be created by many types of cells, but are used most extensively by the nervous system for communication between neurons and to transmit information from neurons to other body tissues such as muscles and glands.

The newly discovered human cells, named «cord - blood - derived embryonic - like stem cells» or CBEs, are not quite as primitive as embryonic stem cells, which can give rise to any tissue type of the body.

Such antibodies, when attached to DNA in complexes, get lodged in the walls of arteries and in tissues to cause inflammation that damages blood vessels, skin, joints and the kidneys as part of the most severe type of lupus, systemic lupus erythematosus (SLE).

Using what's known as multimodal imaging technologies, which combine several methods such as PET - CT and simultaneous measurement, scientists can represent the different types of tissue without penetrating them.

Stem cells have the prized ability to divide and replenish themselves, as well as turn into different types of tissues.

The company's goal is to create a comprehensive source of stem cells that could be of particular use for treating people of Middle Eastern descent, whose tissue types are often underrepresented in the public tissue banks such as those in the U.S. and elsewhere.

To explore these questions Akiko Iwasaki, professor of immunobiology and investigator of the Howard Hughes Medical Institute, and her co-authors observed replication of the Zika virus in the vaginal tissue of control, wild - type mice (genetically unmodified mice) and mice lacking genes that regulate immune system proteins known as type I interferons.

In Arabidopsis, as in most plants, there is a specific zone near the tip of the root where stem cells transition from a stage of proliferation to one where they differentiate into specific tissue types.

Adult stem cells: They have less flexibility and «stemness» to change into different cell types, but they can still produce new cells, specialized to become part of a particular organ or tissue, such as muscle cells or neural cells.

The excess scar tissue that forms as a result of this type of hair loss may also explain the higher risk for uterine fibroids, which are characterized by fibrous growths in the lining of the womb.

Historically, clinicians evaluating a patient for transplant have sought to identify donor cells that are perfectly matched to the patient's cell type, which is considered to be the optimal approach to help ensure successful outcomes and to minimize risk of graft - versus - host disease (GVHD), a serious and potentially life - threatening complication that occurs when the donated immune cells attack the patient's cells as foreign tissue.

Because different types of tissue absorb emissions from the nanotubes differently, the scanner took readings from many locations to triangulate the tumor's exact location, as confirmed by later MRI scans.

There is evidence that chronic disabilities such as spinal cord lesions, diabetes, and Parkinson?s disease, where replacement of just one cell type restores tissue function, can be treated with differentiated embryonic stem cells.

This same feature, tumor heterogeneity, may reduce the ability to identify critical gene expression changes when comparing mean gene expression in adjacent tumor and normal tissues, as tumors of the same type may have different sets of genes differentially expressed.

As «immature» somatic cells, stem cells can mature into different types of cells, thus making them responsible for the development of all the tissues and organs in the body.

Type 3 ILCs (ILC3s) are in addition essential for the development of lymphoid organs such as lymph nodes and for tissue repair.

A study published July 6th in the journal Oncotarget reports on a newly discovered category of tRNA fragments as well as shows that all tRNAs are rich sources of very diverse short molecules whose characteristics depend on a person's gender, population, and race and differ according to tissue and disease type.

Normally, adult stem cells can only morph into the type of tissue in which they reside, such as blood, brain or muscle.

There are two types of fat in humans: white adipose tissue, which makes up nearly all the fat in adults, and brown adipose tissue, which is found in babies but disappears as they age.

To demonstrate the precision of the technique and its ability to generalize to many different human tissue types, the research team created several proof - of - principle organoid arrays mimicking human tissues such as branching vasculature and mammary glands.

These cells — capable of generating all cell types in the body — could be used as the «Lego bricks» to build tissue constructs, larger structures of tissues, and potentially even micro-organs.

«Our work is pointing to reserve stem cells as being the critical players in conferring the benefits of intestinal - tissue regeneration after these types of insults.»

Many tissues of our bodies, such as our skin, can heal because they contain stem cells that can divide and differentiate into the type of cells needed to repair damaged tissue.

The 1 - 3 millimeter granuloma also contains fibrous and necrotic tissue as well as a number of other types of immune cells, making it an extremely complex structure.

So, at the dawn of our universe — and I have to emphasize our universe, because there could be others — so, dawn of our universe, physicists think there was one type of force, one type of matter and that as the cosmos expanded, as space expanded, it cooled and things started to condense out like snow flakes, and over time that single force broke, it differentiated; and something similar happens in the human body as we develop from a single cell; we differentiate, different tissues form in our bodies, different layers of tissues.

Standard tissue engineering involves seeding types of cells, such as those that form ear cartilage, onto a scaffold of a polymer material called a hydrogel.

Basically, when you look at different types of cells, such as fibroblasts, which form connective tissue, or epithelial cells, from saliva, you see general correlations within a person.

But many in the field will be waiting for the next steps: testing whether the resulting mouse pups are genetically normal, trying out the technique in other animals, and using other and less controversial types of cells — such as stem cells that can be extracted and cryopreserved from adult testicular tissue — as the starting point.

Overall, including all genomic variations present in most if not all tumor cells (clonal) as well as those present only in subsets of the cancer cells (subclonal) from tumor tissue, the researchers detected a total of 864 genetic changes in tissue samples across the three tumor types, and 627 (73 %) of those were also found in the blood.

He thinks the data might not move as quickly when travelling through different types of tissue.

He thinks the data might not move as quickly when it has to travel through different types of tissue.

Scientists hope to use stem cells, which can develop into nearly any type of tissue in the body, to treat a variety of diseases as well as to study basic biology (ScienceNOW, 30 November).

This type of minor damage, called «subfailure damage,» is associated with common injuries to connective tissues such as ligament and meniscus tears and various types of tendinitis such as tennis elbow and rotator cuff tendinopathy.

The ability of scientists to convert human skin cells into other cell types, such as neurons, has the potential to enhance understanding of disease and lead to finding new ways to heal damaged tissues and organs, a field called regenerative medicine.

Pluripotent cells can become any of the cell types usually found in the body — although there are certain special types of tissue, such as placenta, that they can't form.

This causes the body's white blood cells to release type 1 interferon - alpha, a small cytokine protein that acts as a systemic alarm, triggering a cascade of additional immune activity as it binds with receptors in different tissues.

Clariom Pico assays can extract data from as little as 100 pg of total RNA, from common and challenging sample types (including formalin - fixed, paraffin - embedded tissues and whole blood) without the need for globin messenger RNA reduction or ribosomal RNA removal.

Compared with adipose tissue of lean individuals, adipose tissue of the obese expresses increased amounts of proinflammatory proteins such as TNF - α, IL - 6, iNOS (also known as NOS2), TGF - β1, C - reactive protein, soluble ICAM, and monocyte chemotactic protein - 1 (MCP - 1)(18 — 25), and procoagulant proteins such as plasminogen activator inhibitor type - 1 (PAI - 1), tissue factor, and factor VII (26 — 28).

This series addresses the contribution of cellular senescence to cardiovascular, neurodegenerative, and arthritic disorders as well as the senescent phenotypes in various tissues and cell types.

The team hopes to apply GLIM technology to human fertility research and treatment, as well as a range of different types of tissue research.

Indeed, in our tissues we found these type of cells are indeed present, and associated with the vasculature as can be seen in the immunohistochemistry for NG2 and PDGF receptor beta.

The researchers examined millions of these genetic code variations, known as single nucleotide polymorphisms (SNPs) and found thousands that control DNA methylation in some or all tissue types.

Scientists describe its stem cells as universal «blank slates,» because each can mature into any type of tissue.

Next - generation «designer matrices» such as hybrid polyethylene glycol hydrogels or microengineered collagen scaffolds, combined with a well - defined set of laminins, may better fulfill the niche requirements of organoids and may be customized for a specific type of tissue / organoid (2,6).

Interleukin 17 is a cytokine that acts as a potent mediator in delayed - type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation, similar to Interferon gamma.

Humans obviously regenerate some cell types very well, such as skin, muscle and liver cells, but almost not at all in cells of the nervous system or with any complex tissue systems.

The authors note that the formation of each different organ bud type may require some fine tuning to optimize tissue self - organization, and further addition of neural cell types may be necessary, but this research may soon provide exciting model systems for the study of basic biology and pathology as well as providing appropriate replacement tissues for the treatment of many patients with no other viable options.

Overton studied the elaborate structures on the surfaces of cells in order to understand how single cells established and maintained connections with their partners as they matured to form different types of tissues in the developing embryo.

«There are other vertebrates, such as zebrafish, bichir and axolotl, which can regenerate many more different types of tissues, including limbs or appendages.