The team hopes to apply GLIM technology to human fertility research and treatment, as well as a range of different
types of tissue research.
Not exact matches
In this
research, Yousaf and his team made a scaffold free beating
tissue out
of three cell
types found in the heart — contractile cardiac muscle cells, connective
tissue cells and vascular cells.
The
research team then examined human pancreatic
tissue from
type 1 diabetics, finding strong evidence that the same process induced by caerulein also occurred in the pancreases
of those individuals.
Building upon their earlier
research on the biology
of fat metabolism, Joslin scientists discovered that microRNAs - small RNA molecules that play important roles in regulation in many
types of tissue — play a major role in the distribution and determination
of fat cells and whole body metabolism.
The latter
type of research, in which human cells or
tissue are integrated into animals, was given the green light in the United Kingdom in October 2008, when the British House
of Commons approved a bill that expanded the country's rules governing work with human embryos.
A portion
of those cells will be banked for that infant's future use in the event
of medical need, with the remainder going to a national public bank for
research and assistance to any patient with a matching
tissue type.
To demonstrate the precision
of the technique and its ability to generalize to many different human
tissue types, the
research team created several proof -
of - principle organoid arrays mimicking human
tissues such as branching vasculature and mammary glands.
This
type of research could also help
tissues heal themselves.
«Our new
type of treatment only targets metastatic
tissue, which enables us to avoid some
of conventional chemotherapy's unwanted side effects,» said Zhao, who is a member
of the Chao Family Comprehensive Cancer Center and the Sue & Bill Gross Stem Cell
Research Center at UCI.
The
research highlights the importance
of investigating different cell
types in normal human
tissues to understand the cellular origin
of cancer and the factors that may contribute to its development.
Praveen Arany at the National Institute
of Dental and Craniofacial
Research in Bethesda, Maryland, and his colleagues wondered if they could use lasers and stem cells to provide a longer - lasting solution, because lasers can make other
tissue types regenerate.
The authors note that the formation
of each different organ bud
type may require some fine tuning to optimize
tissue self - organization, and further addition
of neural cell
types may be necessary, but this
research may soon provide exciting model systems for the study
of basic biology and pathology as well as providing appropriate replacement
tissues for the treatment
of many patients with no other viable options.
We invite original innovative
research on the rational engineering
of plant systems at all levels, including proteins, protein complexes, sensors, metabolic and signalling pathways, microcompartments such as carboxysomes, subcellular compartments, cell
types or
tissues, as well as the engineering
of novel plant hybrid species and the interactions
of plants with viruses, bacteria, and other organisms.
The
research, which appears in the EMBO Journal, indicates that when
tissue responds to certain
types of injury, mature cells seem to get younger and begin dividing rapidly, creating scenarios that can lead to cancer.
In order to measure fat composition, the NYU Langone radiology
research team developed a new approach to magnetic resonance (MR) spectroscopic imaging — a
type of MRI that provides information on the chemical composition
of the
tissue.
New
research has uncovered a missing link in how our body breaks down fat, revealing a set
of nerves that connect with fat
tissue to stimulate the breakdown process in a development that could lead to new
types of anti-obesity treatments.
In a substudy, review outcomes were also compared across different
types of clinical
research, based in large part on the designations and definitions derived from a number of sources, including a report by Nathan, 14 the Institute of Medicine, 20 the NIH Director's Panel on Clinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified human
research, based in large part on the designations and definitions derived from a number
of sources, including a report by Nathan, 14 the Institute
of Medicine, 20 the NIH Director's Panel on Clinical
Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified human
Research, 9 the Association
of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare
Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified human
Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1
of the following: (1) patient - oriented studies
of mechanisms
of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented
research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified human
research focusing on development
of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies
of normal human behavior); (6) health services
research; and (7) use of deidentified human
research; and (7) use
of deidentified human
tissue.
The Society believes that
research involving the transfer
of a human nucleus into an animal egg will lead to important new knowledge about cell nuclear replacement (CNR) technology and, if it were to prove possible to produce embryonic stem cells by this route, would increase understanding
of how to programme these cells to develop into different
tissue types.
The effort to support
research into stem cells — chameleon - like entities that can morph into many
types of tissue and body parts — has run into many obstacles since it was first became law in January 2004.
«The Notch pathway has been implicated in a number
of malignancies, with different roles that are cell and
tissue -
type dependent,» wrote researchers led by Silvia Licciulli, PhD,
of the Scripps
Research Institute in Jupiter, Florida.
Women may also have more
of a
type of B cell that makes autoantibodies that attack the body's own
tissue, per
research from National Jewish Health in Denver.
Clinicians also conduct clinical
research and three current, ongoing studies include investigations into canine osteosarcoma, the most common bone cancer in dogs; soft
tissue sarcomas, the most common
type of solid tumors in dogs; and feline fibrosarcoma, injection - site tumors in cats.
Research has demonstrated that B. burgdorferi can express many different
types of OspC in a canine infection.2 One study demonstrated that 11 different
types of OspC were present in canine
tissue after exposure to B. burgdorferi carrying Ixodes ticks.