Sentences with phrase «types of tissues from»

These cells protect many types of tissues from infection, but they can also promote chronic inflammatory conditions like Crohn's disease, which specifically targets the intestinal tract.
Adult stem cells were once believed to be more limited than embryonic stem cells, only giving rise to the same type of tissue from which they originated.

Not exact matches

From the embryonic stem cells, the researchers produced a type of tissue called retinal pigment epithelium (RPE).
By comparing the results to cells from paired normal tissue, researchers get a detailed molecular picture of the tumor environment, including the types and activity levels of T cells that are critical to the immunotherapy response.
To develop their «disease in a dish» model, the team took skin cells from patients with Allan - Herndon - Dudley syndrome and reprogrammed them into induced pluripotent stem cells, which then can be developed into any type of tissue in the body.
The team tried this method with two types of body cells: ovarian cells from an adult and connective tissue cells from a fetus.
Fred Hutch and UW scientists compared the two types of CD8 + T cells and found that only the CD8αα + T cells persist in the skin while CD8αβ + T cells diminished from the tissue after healing of a herpes lesion.
In past projects, scientists have tried to derive various types of differentiated cells from stem cells — such as bone, tissue, nerves or fat — directly from hiPSCs.
The researchers also found that arteries and veins from the macaques» hearts grew into the new heart tissue, the first time it has been shown that blood vessels from a host animal will grow into and nurture a large stem - cell derived graft of this type.
Action potentials can be created by many types of cells, but are used most extensively by the nervous system for communication between neurons and to transmit information from neurons to other body tissues such as muscles and glands.
ERRORS have occurred in a type of stem cell that could be used instead of embryonic stem cells — and in tissues made from them.
The research team then examined human pancreatic tissue from type 1 diabetics, finding strong evidence that the same process induced by caerulein also occurred in the pancreases of those individuals.
These so - called pluripotent stem cells can be derived from a variety of adult cells and be guided into almost any other tissue type.
Last week, scientists at Harvard University and Columbia University announced that they had proved the viability of a new way to study a disease — amyotrophic lateral sclerosis — by reprogramming cells from a patient to become pluripotent stem cells, which can then become any type of cell or tissue.
Gaining confidence that their compound was appropriately targeting the plaques, the researchers worked with the National Institutes of Health to obtain brain tissue from people who died of Alzheimer's and performed the same type of staining.
Using tissue samples from five wild Amur tigers that died or were destroyed due to neurological disease in 2001, 2004, or 2010, McAloose and her colleagues proved that infection with CDV, a type of morbillivirus, is to blame for the deaths of two of the tigers and caused a serious infection in a third.
The UCLA team identified 353 DNA markers from 51 types of cells and tissues and examined how age affects their DNA methylation levels throughout a lifetime.
To streamline this process, Uhlén's team has created standardized arrays containing microscopic samples from 48 kinds of normal human tissue and 20 types of tumors.
In Arabidopsis, as in most plants, there is a specific zone near the tip of the root where stem cells transition from a stage of proliferation to one where they differentiate into specific tissue types.
The researchers next will turn to analyzing the presence of myoferlin in samples from numerous human tumor types available in an Ohio State tissue bank, which will allow them to compare protein levels in tumors to clinical outcomes for the patients who provided the samples.
«This tells you that all the different types of stromal cells in breast tissue are affected by the GT198 mutation because they all come from a common progenitor cell.»
The results help fill in the scientific puzzle kicked off by Dolly's cloning, which proved that mammalian egg cells were capable of dissolving the genetic roadblocks that limit the potential of most adult cells to give rise to only a single type of tissue — that of the organ from which they hail — whereas embryonic stem cells have the potential to become virtually any kind of body tissue.
To help the new organ withstand the assault from the recipient's natural defenses, doctors developed tissue type matching, a technique to determine if the chemistry of the donor's immune system, defined by antigens on the surface of cells, was similar to that of the recipient's.
For the first time ever, we could make a really comprehensive comparison of individual normal and tumour cells from the exact same type of tissue, taken at the same time, from the same person, and see how the cancer had developed.»
To illuminate the process, the Yale team sequenced normal, primary, and metastatic tumor tissue from multiple individuals, including subjects with a range of cancer types.
The scientists analyzed a variety of sweetpotato tissue types (mature leaves, young leaves, young petioles, buds, vine sections, and root tissue) from a sweetpotato plot at Louisiana State University in late October and again the following September.
The cell, taken from the embryo between the zygote and blastocyst stages, can be collected without damaging the embryo, and yet it is still versatile enough to give rise to whole classes of tissue types.
Because different types of tissue absorb emissions from the nanotubes differently, the scanner took readings from many locations to triangulate the tumor's exact location, as confirmed by later MRI scans.
An international team of scientists, led by Monash Biomedicine Discovery Institute researcher Dr Di Yu, and Dr Axel Kallies from the Walter and Eliza Hall Institute, have discovered that killer T cells, a specialised type of white blood cells, can find these «hidden» infected cells in tissue and destroy them.
Isolated and grown from the patients» fat, these specialized cells have the potential to develop into several different types of tissue.
Scientists have demonstrated a method for generating several key types of eye tissue from human stem cells in a way that mirrors whole eye development.
They also hope to use what they learn from simple models of different tissue types to ultimately build functional human tissues like lung and kidney and neural circuits using larger - scale techniques.
Stem cells obtained from human embryos seem to offer the best chance of new therapies, because unlike other stem cells they have the ability to morph into almost any type of tissue.
Two teams of scientists suggest that activating immune cells in fat can convert the tissue from a type of fat that stores energy to one that burns it, opening up potential new therapies for obesity and diabetes.
Epigenomic profiling of complex tissues obscures regulatory elements that distinguish one cell type from another, researchers report.
«Our group pioneered the development of cell culture technology for harvesting large numbers of stem cells from human bone marrow and human umbilical cord blood,» Dr. Yeh said, noting that stem cells from these two sources are abundant and can be guided into different types of cells using tissue engineering.
«These types of tissue are incredibly difficult to get from healthy living donors,» Engelhardt said.
The researchers focused on the secondary cell walls in a type of plant tissue called xylem from the Arabidopsis plant's roots.
So, at the dawn of our universe — and I have to emphasize our universe, because there could be others — so, dawn of our universe, physicists think there was one type of force, one type of matter and that as the cosmos expanded, as space expanded, it cooled and things started to condense out like snow flakes, and over time that single force broke, it differentiated; and something similar happens in the human body as we develop from a single cell; we differentiate, different tissues form in our bodies, different layers of tissues.
They have enormous clinical potential; unlike stem cells isolated from adult tissue that have been the basis of stem cell treatments so far, hESCs can be grown into any of the body's 200 tissue types.
The nose is lined with sensory tissue, the olfactory epithelium, that contains various types of cells, all of which arise from olfactory stem cells (green).
Scientists had high hopes for reprogrammed stem cells, which could be derived from a patient's own tissue and grown into any type of cell in the body.
Basically, when you look at different types of cells, such as fibroblasts, which form connective tissue, or epithelial cells, from saliva, you see general correlations within a person.
But many in the field will be waiting for the next steps: testing whether the resulting mouse pups are genetically normal, trying out the technique in other animals, and using other and less controversial types of cells — such as stem cells that can be extracted and cryopreserved from adult testicular tissue — as the starting point.
The researchers profiled the microRNA in samples of blood and heart tissue from healthy people and people suffering from one of two types of heart failure, which develops when the heart's pumping action weakens, making it unable to deliver blood throughout the body.
Then they rerouted blood vessels and one or more types of nerves to the transplanted tissue from the nonparalyzed side of the face.
Overall, including all genomic variations present in most if not all tumor cells (clonal) as well as those present only in subsets of the cancer cells (subclonal) from tumor tissue, the researchers detected a total of 864 genetic changes in tissue samples across the three tumor types, and 627 (73 %) of those were also found in the blood.
Clariom Pico assays can extract data from as little as 100 pg of total RNA, from common and challenging sample types (including formalin - fixed, paraffin - embedded tissues and whole blood) without the need for globin messenger RNA reduction or ribosomal RNA removal.
Phages, shown here surrounding and attacking a bacterial cell, are part of a newly discovered type of immunity that protects mucus - covered human tissue from bacterial infection.
A group that included researchers at the Wellcome Trust Sanger Institute and the University of Cambridge, both in the United Kingdom, developed a possible treatment for A1ATD by first reprogramming a skin cell from a patient into iPS cells, which are embryonic - like cells that can develop into many tissue types.
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