These cells protect many
types of tissues from infection, but they can also promote chronic inflammatory conditions like Crohn's disease, which specifically targets the intestinal tract.
Adult stem cells were once believed to be more limited than embryonic stem cells, only giving rise to the same
type of tissue from which they originated.
Not exact matches
From the embryonic stem cells, the researchers produced a
type of tissue called retinal pigment epithelium (RPE).
By comparing the results to cells
from paired normal
tissue, researchers get a detailed molecular picture
of the tumor environment, including the
types and activity levels
of T cells that are critical to the immunotherapy response.
To develop their «disease in a dish» model, the team took skin cells
from patients with Allan - Herndon - Dudley syndrome and reprogrammed them into induced pluripotent stem cells, which then can be developed into any
type of tissue in the body.
The team tried this method with two
types of body cells: ovarian cells
from an adult and connective
tissue cells
from a fetus.
Fred Hutch and UW scientists compared the two
types of CD8 + T cells and found that only the CD8αα + T cells persist in the skin while CD8αβ + T cells diminished
from the
tissue after healing
of a herpes lesion.
In past projects, scientists have tried to derive various
types of differentiated cells
from stem cells — such as bone,
tissue, nerves or fat — directly
from hiPSCs.
The researchers also found that arteries and veins
from the macaques» hearts grew into the new heart
tissue, the first time it has been shown that blood vessels
from a host animal will grow into and nurture a large stem - cell derived graft
of this
type.
Action potentials can be created by many
types of cells, but are used most extensively by the nervous system for communication between neurons and to transmit information
from neurons to other body
tissues such as muscles and glands.
ERRORS have occurred in a
type of stem cell that could be used instead
of embryonic stem cells — and in
tissues made
from them.
The research team then examined human pancreatic
tissue from type 1 diabetics, finding strong evidence that the same process induced by caerulein also occurred in the pancreases
of those individuals.
These so - called pluripotent stem cells can be derived
from a variety
of adult cells and be guided into almost any other
tissue type.
Last week, scientists at Harvard University and Columbia University announced that they had proved the viability
of a new way to study a disease — amyotrophic lateral sclerosis — by reprogramming cells
from a patient to become pluripotent stem cells, which can then become any
type of cell or
tissue.
Gaining confidence that their compound was appropriately targeting the plaques, the researchers worked with the National Institutes
of Health to obtain brain
tissue from people who died
of Alzheimer's and performed the same
type of staining.
Using
tissue samples
from five wild Amur tigers that died or were destroyed due to neurological disease in 2001, 2004, or 2010, McAloose and her colleagues proved that infection with CDV, a
type of morbillivirus, is to blame for the deaths
of two
of the tigers and caused a serious infection in a third.
The UCLA team identified 353 DNA markers
from 51
types of cells and
tissues and examined how age affects their DNA methylation levels throughout a lifetime.
To streamline this process, Uhlén's team has created standardized arrays containing microscopic samples
from 48 kinds
of normal human
tissue and 20
types of tumors.
In Arabidopsis, as in most plants, there is a specific zone near the tip
of the root where stem cells transition
from a stage
of proliferation to one where they differentiate into specific
tissue types.
The researchers next will turn to analyzing the presence
of myoferlin in samples
from numerous human tumor
types available in an Ohio State
tissue bank, which will allow them to compare protein levels in tumors to clinical outcomes for the patients who provided the samples.
«This tells you that all the different
types of stromal cells in breast
tissue are affected by the GT198 mutation because they all come
from a common progenitor cell.»
The results help fill in the scientific puzzle kicked off by Dolly's cloning, which proved that mammalian egg cells were capable
of dissolving the genetic roadblocks that limit the potential
of most adult cells to give rise to only a single
type of tissue — that
of the organ
from which they hail — whereas embryonic stem cells have the potential to become virtually any kind
of body
tissue.
To help the new organ withstand the assault
from the recipient's natural defenses, doctors developed
tissue type matching, a technique to determine if the chemistry
of the donor's immune system, defined by antigens on the surface
of cells, was similar to that
of the recipient's.
For the first time ever, we could make a really comprehensive comparison
of individual normal and tumour cells
from the exact same
type of tissue, taken at the same time,
from the same person, and see how the cancer had developed.»
To illuminate the process, the Yale team sequenced normal, primary, and metastatic tumor
tissue from multiple individuals, including subjects with a range
of cancer
types.
The scientists analyzed a variety
of sweetpotato
tissue types (mature leaves, young leaves, young petioles, buds, vine sections, and root
tissue)
from a sweetpotato plot at Louisiana State University in late October and again the following September.
The cell, taken
from the embryo between the zygote and blastocyst stages, can be collected without damaging the embryo, and yet it is still versatile enough to give rise to whole classes
of tissue types.
Because different
types of tissue absorb emissions
from the nanotubes differently, the scanner took readings
from many locations to triangulate the tumor's exact location, as confirmed by later MRI scans.
An international team
of scientists, led by Monash Biomedicine Discovery Institute researcher Dr Di Yu, and Dr Axel Kallies
from the Walter and Eliza Hall Institute, have discovered that killer T cells, a specialised
type of white blood cells, can find these «hidden» infected cells in
tissue and destroy them.
Isolated and grown
from the patients» fat, these specialized cells have the potential to develop into several different
types of tissue.
Scientists have demonstrated a method for generating several key
types of eye
tissue from human stem cells in a way that mirrors whole eye development.
They also hope to use what they learn
from simple models
of different
tissue types to ultimately build functional human
tissues like lung and kidney and neural circuits using larger - scale techniques.
Stem cells obtained
from human embryos seem to offer the best chance
of new therapies, because unlike other stem cells they have the ability to morph into almost any
type of tissue.
Two teams
of scientists suggest that activating immune cells in fat can convert the
tissue from a
type of fat that stores energy to one that burns it, opening up potential new therapies for obesity and diabetes.
Epigenomic profiling
of complex
tissues obscures regulatory elements that distinguish one cell
type from another, researchers report.
«Our group pioneered the development
of cell culture technology for harvesting large numbers
of stem cells
from human bone marrow and human umbilical cord blood,» Dr. Yeh said, noting that stem cells
from these two sources are abundant and can be guided into different
types of cells using
tissue engineering.
«These
types of tissue are incredibly difficult to get
from healthy living donors,» Engelhardt said.
The researchers focused on the secondary cell walls in a
type of plant
tissue called xylem
from the Arabidopsis plant's roots.
So, at the dawn
of our universe — and I have to emphasize our universe, because there could be others — so, dawn
of our universe, physicists think there was one
type of force, one
type of matter and that as the cosmos expanded, as space expanded, it cooled and things started to condense out like snow flakes, and over time that single force broke, it differentiated; and something similar happens in the human body as we develop
from a single cell; we differentiate, different
tissues form in our bodies, different layers
of tissues.
They have enormous clinical potential; unlike stem cells isolated
from adult
tissue that have been the basis
of stem cell treatments so far, hESCs can be grown into any
of the body's 200
tissue types.
The nose is lined with sensory
tissue, the olfactory epithelium, that contains various
types of cells, all
of which arise
from olfactory stem cells (green).
Scientists had high hopes for reprogrammed stem cells, which could be derived
from a patient's own
tissue and grown into any
type of cell in the body.
Basically, when you look at different
types of cells, such as fibroblasts, which form connective
tissue, or epithelial cells,
from saliva, you see general correlations within a person.
But many in the field will be waiting for the next steps: testing whether the resulting mouse pups are genetically normal, trying out the technique in other animals, and using other and less controversial
types of cells — such as stem cells that can be extracted and cryopreserved
from adult testicular
tissue — as the starting point.
The researchers profiled the microRNA in samples
of blood and heart
tissue from healthy people and people suffering
from one
of two
types of heart failure, which develops when the heart's pumping action weakens, making it unable to deliver blood throughout the body.
Then they rerouted blood vessels and one or more
types of nerves to the transplanted
tissue from the nonparalyzed side
of the face.
Overall, including all genomic variations present in most if not all tumor cells (clonal) as well as those present only in subsets
of the cancer cells (subclonal)
from tumor
tissue, the researchers detected a total
of 864 genetic changes in
tissue samples across the three tumor
types, and 627 (73 %)
of those were also found in the blood.
Clariom Pico assays can extract data
from as little as 100 pg
of total RNA,
from common and challenging sample
types (including formalin - fixed, paraffin - embedded
tissues and whole blood) without the need for globin messenger RNA reduction or ribosomal RNA removal.
Phages, shown here surrounding and attacking a bacterial cell, are part
of a newly discovered
type of immunity that protects mucus - covered human
tissue from bacterial infection.
A group that included researchers at the Wellcome Trust Sanger Institute and the University
of Cambridge, both in the United Kingdom, developed a possible treatment for A1ATD by first reprogramming a skin cell
from a patient into iPS cells, which are embryonic - like cells that can develop into many
tissue types.