Not exact matches
They found higher levels of JAK1 in resistant tumors, which caused increased
expression of epidermal growth factor receptor (EGFR)-- a receptor
tyrosine kinase that promotes cell proliferation.
Gene
expression in papillary thyroid carcinomas, with special reference to
tyrosine kinase receptors and growth factors.
We also noted constitutive surface
expression of the
tyrosine kinase receptors Tie - 2, FGFR - 1, and Flk - 1 on proliferating and resting endothelial cells (data not shown).
Expression of the receptor
tyrosine kinase Tie2 in neoplastic glial cells is associated with integrin beta1 - dependent adhesion to the extracellular matrix.
Further, we identified a role for ABL
kinases in promoting the
expression of multiple pro — bone metastasis genes such as AXL (which encodes a receptor
tyrosine kinase), IL6 (which encodes interleukin - 6), MMP1 (which encodes matrix metalloproteinase 1), and TNC (which encodes tenascin - C) through TAZ - and signal transducer and activator of transcription 5 (STAT5)-- mediated signaling.
Of particular note were decreased mGluR5 and
Tyrosine Kinase c - kit and increased IBA1, CD68, ICAM1, VEGF - D, and TLR4 mRNA
expression in Tsc1GFAPCKO mice.
Investigated TAM family receptor
tyrosine kinase gene
expression in response to small molecule inhibitors in glioblastoma multiforme