Sentences with phrase «tyrosine phosphorylation as»

Importantly, stimulation of the crosslinking of CD4ζ chimeric receptors led to tyrosine phosphorylation as would be expected for a fully functional chimeric receptor.

Not exact matches

The sequence similarity between MAD - 3 and pp40 includes a casein kinase II and consensus tyrosine phosphorylation site, as well as five repeats of a sequence found in the human erythrocyte protein ankyrin.

Similarly, increased level of STAT2 tyrosine phosphorylation was detected as well in IRF - 1 — transfected HT1080 cells (Fig. 4B).

Here, we have shown for the first time that the unphosphorylated STAT2 could play an important role in RIG - G gene expression by interacting with IRF - 9, further reinforcing the idea that STAT proteins could function as transcription factors in the absence of tyrosine phosphorylation.