Sentences with phrase «ubiquitin attachment»

The team sought to identify how BRCA1 manages to perform the ubiquitin attachment role, and found that it relies on a part of a partner protein, called BARD1.

Not exact matches

The new research has found that this attachment of ubiquitin by BRCA1, its «ubiquitin ligase activity», is needed for a specific type of DNA repair that is «error - free», known as homologous recombination.

If — as in the eukaryotic ubiquitin - based system — the access to the protease depends on a specific tag that must be carried by the substrate, then the important decision who and when should be eliminated boils down to the timely and selective attachment of tags.

The signal for such destruction is provided by attachment of a small ubiquitous protein tag, called ubiquitin.