The evolving role of
ubiquitin modification in endoplasmic reticulum - associated degradation
Ubiquitin modification can result in a number of different effects.
The researchers performed studies to determine how
ubiquitin modification changes SIRT1 function.
They discovered that cells respond to
ubiquitin modification of SIRT1 differently according to the type of environmental insult that occurs.
Not exact matches
We show that oxidative
modifications of
ubiquitin carboxyl - terminal hydrolase L1 (UCH - L1), γ - enolase, actin, and dimethylarginine dimethylaminohydrolase 1 (DMDMAH - 1) are present in the brain of familial AD... subjects.
Modification of proteins by the small
ubiquitin - like modifier SUMO is a dynamic and reversible process.
As such, it appears that the insulin / IGF - PI 3K pathway not only regulates myofibrillar cleavage through caspase 3, but also the ubiquitylation of the resulting protein fragments via
modification of
ubiquitin - ligase expression.