Sentences with phrase «ubiquitin molecules»

Several years later, Varshavsky showed how the individual ubiquitin molecules hook up in these chains.
To achieve this, the research team devised a system that expresses two genetically engineered ubiquitin molecules at once.
When both halves of Kusabira Green are next to each other, green light is emitted — so the net result is that a cell will light up wherever the two ubiquitin molecules are attached to one another.
The addition of many ubiquitin molecules can target a protein for degradation, while the addition of a single ubiquitin molecule (monoubiquitination) can lead to activation of protein signaling pathways or target other proteins for ubiquitination.
PTEN tagged with multiple ubiquitin molecules can then be recognized and destroyed by the cell's protein degradation machinery.
Proteins can be regulated by a process called ubiquitination, in which an ubiquitin molecule is added to a protein.
Moffitt researchers performed molecular studies to show for the first time that SETDB1 is constitutively modified by a single ubiquitin molecule.

Not exact matches

In the affected children, the inability to remove the ubiquitin proteins from various molecules resulted in an increased production of chemical messengers that lead to inflammation (inflammatory cytokines).
When it does, molecules called ubiquitins mark the duds for destruction.
Enzymes in this family couple other proteins in the cell to a molecule called ubiquitin, a step that can alter the function or stability of these target proteins.
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