Sentences with phrase «uncapped ends of chromosomes»
The researchers suspected that early damage from exonucleases might be going unnoticed because the uncapped ends of chromosomes fuse soon afterward.
http://www.sciencemag.org/ Not exact matches
Furthermore, by chromatin immunoprecipitation and whole - genome scanning approaches, we show that the chromosome ends of senescent cells directly contribute to the DNA damage response, and that uncapped telomeres directly associate with many, but not all, DNA damage response proteins.