Sentences with phrase «uncertain future conditions»

These additional datasets will also help individuals understand how the changing climate affects public health in their area, risk factors that make a person more vulnerable to climate - related health effects, and how to plan for uncertain future conditions.

Not exact matches

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

IJC officials applaud the $ 22 million the state allocated to help communities, business and homeowners recover from flooding, but they cautioned that future climate conditions are uncertain and that extreme water levels could happen again and more often.

It is a simple, but counterintuitive idea: Under the right conditions, losing stocks — those in crisis, with apparently failing businesses, and uncertain futures — offer unusually favorable investment prospects.

Bonds with long maturities also carry more risk since conditions years in the future are more uncertain than in the short term.

This panel discussion will address questions of how artists use digital technology to mark current conditions and evoke uncertain futures — How can we make future climate change seem real to the present?

They are also used to explore the implications of climate change for decision making (e.g., exploring whether plans to develop water management infrastructure are robust to a range of uncertain future climate conditions).

As we face an uncertain climatic future, the past can provide some illumination of possible changing conditions, and a combination of data and modeling brings the best of science together.

Disclaimer Forecasts of potential occurrences or non-occurrences of future conditions and events are inherently uncertain.