Not exact matches
A Perth company that has become a global leader in the education software
market is facing
uncertain times as main rival Blackboard takes over two of its biggest partners.
At the best of
times, everything a CMO does is a gamble with ephemeral and
uncertain results; that's a hundred
times truer now, with
marketing tools multiplying faster than anyone could truthfully claim to keep up with.
Actual results and the
timing of events could differ materially from those anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the
uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected
times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the
uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources;
market competition; changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website at www.sec.gov.
These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings;
market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an
uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other
market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from
time to
time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
As the advertising
market remains
uncertain, the
Times is relying more on its readers to support its journalism.
Given the
uncertain state of play, Aereo is of limited use to
Time Warner Cable currently; along with New York, the fight with CBS affects subscribers in Los Angeles, Dallas and several smaller
markets.
Trump's public comments serve only to create uncertainty in the
market at an already
uncertain time for many farmers, he said.
Market volatility will wreak havoc with day - to - day valuations, but if the business or underlying assets that generate the income are fundamentally sound, then we know with confidence that the cash flow from our model portfolio won't be radically interrupted during
uncertain times.
They become especially useful during
times of
market volatility when prices might be
uncertain.
The problem is that this process is unprecedented, will take considerable
time to complete and it outcome is necessarily
uncertain — points of risk were spelled out pretty clearly in the latest bidder statement Murray Goulburn offered the
market on Monday.
In the
uncertain, often volatile oil
market, it is difficult to predict long - term fuel costs, and more specifically, costs at the
time of the voyage.
In the
uncertain, often volatile global oil
market, it is difficult to predict long - term fuel costs and, more specifically, costs at the
time of the trip.
At the same
time, E-Ink, which currently manufactures most of the displays for the existing e-readers in the
market, is also engaged in developing color displays, although its quite
uncertain whether they would be able to release such a product before 2011.
The Android tablet
market has been staring at an
uncertain future for some
time now.
At the same
time,
uncertain market prospects mean paying close attention to cost to meet return targets is important.
«One of the tricky things about studying
market history is that what looks inevitable to us now was
uncertain to every single investor at the
time.»
Exchanges temporarily suspend this minimum price requirement during
uncertain times; for example, the New York Stock Exchange (NYSE) and Nasdaq suspended the minimum $ 1 price requirement for stocks listed during the 2008 - 09 bear
market.
However, it's worth highlighting fresh anxieties over Chinese / emerging
market growth mean the
timing of this convergence has become that much more
uncertain... On the other hand, CRH is still the Irish blue chip for domestic & international investors (well, even though it's not very Irish...)-- so I'll continue to assign a 0.7 P / S multiple.
My investment horizon is medium to long term (> 5 years) with 11 - 12 % expected returns, but
uncertain about entering the
markets at the current «all
time high» levels.
This has happened a number of
times before but one of the interesting things about today is that the
market seems not only
uncertain but downright jittery.
A: yes, it would, but the
timing and amount of liquidations are
uncertain, and the «
market prices» don't really exist for the underlying — they are too influenced by Third Avenue's holdings.
Timing of fossil fuels being superceded across the various
markets will be
uncertain, but investors should be cognisant of the dangers and consider their portfolios accordingly — the risk premium of fossil fuel project development has been raised.
That arguably sums up why law firms like energy deals so much right now — they are a welcome presence in the deal
market, providing a steady stream of work in
uncertain times.
The vast majority of respondents (78 %) were of the view that Theresa May is the best leader for the country during these
uncertain times, while most respondents (75 %) believe Britain needs to retain access to the Europe's single
market in order to be successful.
All in all, the move comes during an
uncertain time for the cryptocurrency
market, which has seen a period of sideways trading following a torrid first half in 2017.
The Android tablet
market has been staring at an
uncertain future for some
time now.
I hope that the Hays Global Skills Index 2017 provides not only a useful insight into the worldwide labour
market, but some food for thought on how business can navigate
uncertain times and ensure people and talent are at the heart of business strategies for growth and success in the years to come.
The Hays UK Salary & Recruiting Trends 2018 guide shows that 69 % of
marketing employers expect to hire in the next year, a positive figure in otherwise
uncertain times.
Her genuine desire to help others while «making a difference» eases their burden during these
uncertain times and builds the confidence clients require to
market themselves strategically.For 11 years, Darlene's expertise was heavily relied upon in
marketing, administration, and quality control within the financial services industry.
Usually, the path for a new business venture is rather
uncertain and a lot depends on
timing and
market readiness.
«The biggest hurdle to closing in an
uncertain market is the lack of comps, especially for FHA and VA loans that require comps to be within a three - month
time limit,» says John Mijac, e-PRO, GRI, with Old Adobe Realty in Tucson, Ariz..
During
uncertain times, buyers will not stick their neck out to purchase a high priced home in a
market rated as the most likely to crash.
In this increasingly
uncertain market environment, banks are looking to close the loans that make the most business sense, on properties that will hold their value over
time.
Since the
timing of the disposition of foreclosed properties can be highly
uncertain, we will witness choppy price movements as individual metro
markets stabilize.
In these
uncertain times, many home owners have had to face the fact that the current
market value of their homes is less than they once thought.
This might be the most
uncertain time in the US in a long
time - what's your
market doing?
Although moving from the beloved family home is often a difficult and emotional process, our full service approach — rooted in a deep understanding of residential and senior housing
markets, alleviates the stress and anxiety commonly experienced during these
uncertain times.