Sentences with phrase «uncertain over the future»

Add uncertainty over Giroud and that's 4 of our front 5 that are uncertain over their future.

Not exact matches

Fundamentally, buying insurance means giving up a small certain payment today - or in regular installments over time - to ensure that a larger, uncertain payment is not required in the future.

For example, the anxious group read sentences like «safety is not guaranteed in our neighborhoods nor in our own homes,» which was intended to highlight the «lack of control over negative circumstances that may happen in life and an uncertain future,» according to the study.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

The future of bitcoin is uncertain, but with continuous positive gains over the past several years and an expanding interest in the development of blockchain, the technology is set to bring change to society in one way or another.

Updated Elders chief executive Mark Allison says the 175 - year - old pastoral company is now back on a growth path and the dark days of being debt - plagued and hobbling along with an uncertain future are over.

Jose Mourinho faces an uncertain future at Manchester United following an interview over the weekend in which he appeared to flirt with the prospect of managing Paris Saint - Germain.

There has been speculation over the future of both players in recent weeks, and it is uncertain whether they will remain at Stamford Bridge beyond this transfer window.

Alexis has been the stand - out star in North - London over the past couple of seasons, and that doesn't look set to change despite his uncertain future.

Fabregas» future remained «uncertain» in the media's eyes over the summer, with Manchester United and David Moyes rather comically seeking to bring in the midfielder.

Their dilemma is over whether to implement further structural reform in the frame of the Eurozone, knowing that these measures could take longer to take effect than what is politically acceptable, or exit the Euro in order to regain competitiveness through a sharp currency devaluation and face huge upfront costs and an uncertain future.

The future of all these stores is uncertain, though the company says it's refinancing and hopes to turn things around over the next year.

Negotiations over the future of the 421 - a development tax break are improving after they stalled for months in the fall, though a deal remains uncertain by the Jan. 15.

However it is important that any decisions about a change of status for a school are taken for sound educational reasons, not because of misunderstanding over the current law or fear of an uncertain future.

And while there was much celebration over the improved numbers, still a quarter of all LA Unified seniors, perhaps as many as 10,000, would not celebrating in commencement ceremonies and would be facing uncertain futures.

Five years ago, the book world was seized by collective panic over the uncertain future of print.

I hear about authors who are reduced to shadows of their former selves because poor sales or dysfunctional relationships or even fears over an uncertain future have made them doubt — their talent, maybe, or their ability to persevere within the business for any number of reasons.

HP's TouchPad, amidst a firesale earlier this year and an uncertain future, managed to grab third place after selling just over 900,000 units, securing 5 percent of the market.

Because the interest rate on an ARM is uncertain once the fixed - rate period is over, APR estimates can severely understate the actual borrowing costs if mortgage rates rise in the future.

The recent fight over the just - passed tax reform package, current budget proposals from the Trump administration, and legislation just introduced into Congress all point to an uncertain future for student borrowers.

The landscape of retirement has changed dramatically over the last few decades, however, and with traditional pension plans dwindling, the future of Social Security uncertain, the rising costs of health care, and now retirement right around the corner, people are rethinking their approach to retirement income.

Hey Sunny I was looking over your non-registered portfolio for the purpose of identifying growth companies that have i) had a great run and whose outlook is not great i.e. high PE or PEG valuation or ii) companies that have gone south price wise and their future uncertain due to wayward mismanagement etc.Since purchasing many of these during the financial crisis, some unsystematic or systematic risks may be around the corners that will bring down your capital gain drastically.

A very fun evening with Cat lovers from all over the area joining us to raise money for our organization, which has helped save many cats from a uncertain future.

> Sydney Biennale 21Mar - 9Jun + George Brandis, Arts Minister, urges penalty for arts organisations rejecting corporate sponsorship smh + Biennale of Sydney future in doubt as chairman Luca Belgiorno - Nettis resigns over disputed links to detention centres dailytelegraph + Biennale of Sydney facing uncertain future after severing ties with its founding partner Transfield smh + Artists» detention protest hits Biennale theaustralian + Five artists have withdrawn from the Sydney Biennale artshub + Libia Castro en colaboración con el artista Ólafur Ólafsson biennaleofsydney + video > Sydney Biennale: exploring a city filled with art guardian

> Sydney Biennale 21Mar - 9Jun > Biennale of Sydney future in doubt as chairman Luca Belgiorno - Nettis resigns over disputed links to detention centres dailytelegraph > Biennale of Sydney facing uncertain future after severing ties with its founding partner Transfield smh > Artists» detention protest hits Biennale theaustralian + Five artists have withdrawn from the Sydney Biennale artshub

> Sydney Biennale 21Mar - 9Jun + George Brandis, Arts Minister, urges penalty for arts organisations rejecting corporate sponsorship smh + Biennale of Sydney future in doubt as chairman Luca Belgiorno - Nettis resigns over disputed links to detention centres dailytelegraph + Biennale of Sydney facing uncertain future after severing ties with its founding partner Transfield smh + Artists» detention protest hits Biennale theaustralian + Five artists have withdrawn from the Sydney Biennale artshub

A monumental mobile by Alexander Calder, one of the 20th century's great artists, began to disappear from its decades - old home in Willis Tower's lobby Monday, headed for an art storage facility and an uncertain future because of a legal dispute over...

«Future generations will wonder in bemused amazement that the early 21st century's developed world went into hysterical panic over a globally averaged temperature increase of a few tenths of a degree, and, on the basis of gross exaggerations of highly uncertain computer projections combined into implausible chains of inference, proceeded to contemplate a roll - back of the industrial age,» Lindzen was quoted, offering praise for Christopher C. Horner's Politically Incorrect Guide to Global Warming and Environmentalism.

EIA recognizes that projections over a 25 - year horizon are inherently uncertain and subject to changing policy objectives, supply disruptions, the emergence of disruptive technologies, and other future developments.

But in the face of climate change, long - term planning (over several decades) is needed for a future that is highly uncertain.

It is characterized by multiple intersecting and uncertain future hazards to natural and human systems, that are expected to unfold over a very large range of spatial and temporal scales, and whose probabilities may be difficult, or in some cases impossible, to quantify precisely (because of intrinsic and / or irreducible uncertainties about the future).

With expectations getting lowered all over the place, the future of any truly productive results uncertain, and peaceful protests rising up with greater force — and police using force to beat them back — the legacy of the COP15 climate talks is entirely up in the air.

With expectations getting lowered all over the place, the future of any truly productive results uncertain, and peaceful protests rising up with greater force — and police using force to beat them back — the legacy of the COP15

«We are in effect forced to make current decisions about highly uncertain events in the distant future even though these estimates are highly speculative and are almost sure to be refined over the coming decades.»

The landscape of retirement has changed dramatically over the last few decades, however, and with traditional pension plans dwindling, the future of Social Security uncertain, the rising costs of health care, and now retirement right around the corner, people are rethinking their approach to retirement income.

While the capabilities of future technology are uncertain, there are strong reasons to believe that devolving more decision making over targeting to weapons systems themselves will erode the fundamental obligation that rules of international humanitarian law (IHL) and international human rights law be applied by people, and with sufficient specificity to make them meaningful.

Over the past several years many people have experienced company layoffs, cutbacks or uncertain futures.

The Full Federal Court found that the first judge had made a number of errors in his decision and have sent the case back for consideration by a new judge, leaving the Noongar peoples uncertain about the future of their rights over the land.

Some anxiety over an uncertain future is natural.

Released at the Midyear Legislative Meetings & Trade Expo in Washington, D.C., the report was compiled from 16 workshops across the country in an effort to answer the question over the future of NAR in uncertain times.