Sentences with phrase «uncertainties involved with»

Of the many uncertainties involved with divorce, child support can be front and center.

The actual paper does discuss the uncertainties involved with the methods....

As similar clinics in other areas have done, we offer walk - in appointments for feral cat caregivers because we understand the uncertainties involved with trapping free - roaming cats.

What are the sources of uncertainty involved with it?

They are a great way to start generating cash - flow and accelerate your journey to financial freedom without the stressors of traditional rentals or the time, labor, and uncertainty involved with flipping.

Not exact matches

Certain matters discussed in this news release are forward - looking statements that involve a number of risks and uncertainties including, but not limited to, doubts about the Company's ability to continue as a going concern, the need to obtain additional funding, risks in product development plans and schedules, rapid technological change, changes and delays in product approval and introduction, customer acceptance of new products, the impact of competitive products and pricing, market acceptance, the lengthy sales cycle, proprietary rights of the Company and its competitors, risk of operations in Israel, government regulations, dependence on third parties to manufacture products, general economic conditions and other risk factors detailed in the Company's filings with the United States Securities and Exchange Commission.

Likewise, Mexico has a total of 10 free trade agreements involving 44 countries outside of NAFTA and Canadian and American companies can find ways to benefit from Mexican global market access in this time of uncertainty with the U.S.

These risks and uncertainties include: Gilead's ability to achieve its anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently anticipated; Gilead's ability to receive regulatory approvals in a timely manner or at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).

The degree of auditor judgment related to areas in the financial statements that involved the application of significant judgment or estimation by management, including estimates with significant measurement uncertainty;

Investors are cautioned that such forward - looking statements involve risks and uncertainties that could cause actual results to differ materially from the anticipated results, and therefore we refer you to a more detailed discussion of the risks and uncertainties in the Company's filings with the Securities and Exchange Commission when available.

Bankers and others involved in business with Iran say they have been reluctant to travel to the country to close deals or negotiate the financing of existing ones because of uncertainty over the status of underlying U.S. sanctions, even before the latest standoff between Trump and Iran.

There are a number of important factors that could cause actual results or events to differ materially from those indicated by such forward - looking statements, including, but not limited to: uncertainties involving interpretation of drilling results, environmental matters, lack of ability to obtain required permitting, equipment breakdown or disruptions, and the other factors described in Paramount's disclosures as filed with the SEC.

Examples of these risks, uncertainties and other factors include, but are not limited to the impact of: adverse general economic and related factors, such as fluctuating or increasing levels of unemployment, underemployment and the volatility of fuel prices, declines in the securities and real estate markets, and perceptions of these conditions that decrease the level of disposable income of consumers or consumer confidence; adverse events impacting the security of travel, such as terrorist acts, armed conflict and threats thereof, acts of piracy, and other international events; the risks and increased costs associated with operating internationally; our expansion into and investments in new markets; breaches in data security or other disturbances to our information technology and other networks; the spread of epidemics and viral outbreaks; adverse incidents involving cruise ships; changes in fuel prices and / or other cruise operating costs; any impairment of our tradenames or goodwill; our hedging strategies; our inability to obtain adequate insurance coverage; our substantial indebtedness, including the ability to raise additional capital to fund our operations, and to generate the necessary amount of cash to service our existing debt; restrictions in the agreements governing our indebtedness that limit our flexibility in operating our business; the significant portion of our assets pledged as collateral under our existing debt agreements and the ability of our creditors to accelerate the repayment of our indebtedness; volatility and disruptions in the global credit and financial markets, which may adversely affect our ability to borrow and could increase our counterparty credit risks, including those under our credit facilities, derivatives, contingent obligations, insurance contracts and new ship progress payment guarantees; fluctuations in foreign currency exchange rates; overcapacity in key markets or globally; our inability to recruit or retain qualified personnel or the loss of key personnel; future changes relating to how external distribution channels sell and market our cruises; our reliance on third parties to provide hotel management services to certain ships and certain other services; delays in our shipbuilding program and ship repairs, maintenance and refurbishments; future increases in the price of, or major changes or reduction in, commercial airline services; seasonal variations in passenger fare rates and occupancy levels at different times of the year; our ability to keep pace with developments in technology; amendments to our collective bargaining agreements for crew members and other employee relation issues; the continued availability of attractive port destinations; pending or threatened litigation, investigations and enforcement actions; changes involving the tax and environmental regulatory regimes in which we operate; and other factors set forth under «Risk Factors» in our most recently filed Annual Report on Form 10 - K and subsequent filings by the Company with the Securities and Exchange Commission.

With the socioeconomical fallout from Brexit still causing uncertainty, plus announcements entailing a complete overhaul of how the industry is regulated and a number of food safety scandals involving big players like 2 Sisters Food Group — 2017 so far has been tumultuous to say the least.

Successfully managing uncertainty involves neither predicting an outcome and hoping you're right or doing nothing with a «wait and see» attitude; rather, it involves laying the groundwork in advance for all likely eventualities.

From the examples chosen a pattern emerges that requires a period of sober reflection by any minister or civil servant involved in the planning of major technological projects, for far from the comfort of scientific truth underpinning their decisions, the reality is that the degree of uncertainty involved would appear to reduce the process to a sophisticated form of gambling, with awesome consequences awaiting a wrong decision.

Coping with this uncertainty involves doing a decent head - job on yourself: blotting it out at least until the time of reckoning draws near.

This means that (1) animals are directly involved in an oxygen - regulating cycle or feedback loop that has previously been overlooked, and (2) we can directly test the idea (despite the uncertainties associated with looking so far back in time) by looking for a decrease in ocean oxygenation in conjunction with the spread of bioturbation.

Any statements contained in this press release that relate to future plans, events or performance are forward - looking statements that involve risks and uncertainties including, but not limited to, those relating to technology and product development, market acceptance, government regulation and regulatory approval processes, intellectual property rights and litigation, dependence on strategic partners, ability to obtain financing, competitive products and other risks identified in deCODE's filings with the Securities and Exchange Commission.

The aspects of assets and liabilities which are studied within a specified diameter of investment and involves considering uncertainty along with investment risk are termed as Finance.

In accordance with the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, the publisher notes that statements contained herein that look forward in time, which include other than historical information, involve risks and uncertainties that may affect the company's actual results of operations.

In accordance with the safe harbor provisions of the Private Securities Litigation Reform Act, statements contained herein that look forward in time, which include everything other than historical information, involve risks and uncertainties.

This release contains forward - looking information that involves substantial risks and uncertainties about the intention to file a registration statement with the U.S. Securities and Exchange Commission for an initial public offering of a minority ownership stake in Pfizer's Animal Health business, including the anticipated timing of such a transaction and the potential benefits to Pfizer.

Thanks to a message in my logbook, I found out how to play the markets (simple buy low and sell high concept), but everything else I met with uncertainty and still don't feel comfortable on the subjects; most of which involve exploration.

Such determinations require careful, quantitative analyses involving forcings estimates and reconstructions, and are fraught with limitations owing to uncertainties in both the forcing estimates and reconstructions — an excellent discussion is provided in this manuscript by Waple et al and references therein.

And, as I write, this whiplash effect transcends journalism, involving scientists, scientific journals, public relations offices, and a public poorly attuned to the rhythms of scientific inquiry and risk management in situations laden with uncertainty.

Regarding ECS («equilibrium climate sensitivity»), I think there are difficulties estimating anything truly resembling a Charney - type ECS from data involving OHC uptake and forcing estimates, because these estimates are fraught with so many uncertainties, and because the values that are calculated, even if accurate, bear an uncertain relationship to how the climate would behave at equilibrium.

Accounting for Both Random Errors and Systematic Errors in Uncertainty Propagation Analysis of Computer Models Involving Experimental Measurements with Monte Carlo Methods.

Now, add all those up, with all the uncertainties involved in trying to get a geographic average when, for example, large swaths of the earth are not covered by an official thermometer, and what is the error on the total?

There are some interesting quotes from climate scientists in this article that highlight a large degree of uncertainty with respect to the climate system, and the human role in it, even among scientists closely involved with the IPCC reports.

Moreover, it tackles squarely what is perhaps the most relevant policy issue at the moment — the potential costs and benefits involved in dealing with scientific uncertainty.»

This ends up changing estimates of cumulative carbon emissions since the pre-industrial period, but given the large uncertainties involved the authors caution against using these revisions to draw conclusions about remaining carbon budgets associated with staying within the 2C or 1.5 C warming targets.

Because of the many uncertainties involved, any estimate of climate sensitivity comes with a range, a lower and upper limit within which the real value could reasonably lie.

A lot of people have different positions in the AGW debate, and with so many people and so much uncertainty particularly about the mechanisms and rate constants of all of the kinetic processes involved, I find it implausible that people would waste time on the simple comparisons, making much sound and fury, when it starts out with a short term comparison of CO2 and temperature over the same last few years.

Fortunately, in one - dimensional cases where uncertainty involves measurement and similar errors it is often possible to find a completely noninformative prior, with the result that exact probability matching can be achieved.

By contrast, a (frequentist) x % one - sided confidence interval with a limit of y can, if accurate, be thought of as one calculated to result in values of y such that, upon indefinitely repeated random sampling from the uncertainty distributions involved, the true parameter value will lie below y in x % of cases.

To this end, Skeptical Science is providing a tool to estimate temperature trends and uncertainties, along with an introduction to the concepts involved.

In addition to having failed on qualitative and quantitative expressions of uncertainty, being susceptible for noble cause corruption, InterAcademy Council seem to have been heavily involved with United Nations and IPCC — both politically, economically, personally and otherwise.

Key uncertainties involve: 1) the degree to which increases in evapotranspiration versus permafrost thaw are leading to drier landscapes; 2) the degree to which it is these drier landscapes associated with permafrost thaw, versus more severe fire weather associated with climate change, that is leading to more wildfire; 3) the degree to which the costs of the maintenance of infrastructure are associated with permafrost thaw caused by climate change versus disturbance of permafrost due to other human activities; and 4) the degree to which climate change is causing Alaska to be a sink versus a source of greenhouse gases to the atmosphere.

Nevertheless, I agree with Pat Michaels on this point — «Given the uncertainties that are involved, the OMB [and NAS, DOE, EPA, etc.] should not act to update the current SCC determination, but rather to discard it in its entirety».

As Pekka points out, there is considerable uncertainty associated with the magnitude of projections, but paleoclimatologic data indicate that they are likely to be sufficient to impair the calcification processes essential for the integrity of many marine species involved in the food chain, and thus of concern to us to the extent that our civilization is linked to the welfare of ocean biology...

Even just acknowledging more openly the incredible magnitude of the deep structural uncertainties that are involved in climate - change analysis — and explaining better to policymakers that the artificial crispness conveyed by conventional IAM - based CBAs [Integrated Assessment Model — Cost Benefit Analyses] here is especially and unusually misleading compared with more ordinary non-climate-change CBA situations — might go a long way toward elevating the level of public discourse concerning what to do about global warming.

Lee breaks new ground (as far as I know, anyways) regarding the ethics of decision making under deep uncertainty, with some profound conclusions regarding mitigation versus adaptation: «I assume here that the greater the speculation and uncertainties involved, the weaker the ethical claim.

The present paper reviews existing knowledge with regard to Organic Aerosol (OA) of importance for global climate modelling and defines critical gaps needed to reduce the involved uncertainties.

For some time all those involved in buying and selling insolvent businesses were faced with uncertainty when one division of the Employment Appeal Tribunal (EAT) suggested that intention had to be judged case by case, depending on the facts.

Perceptions of the many use cases studied suggest that with the exception of uses that earn users money or involve advertising — at least until specific case scenarios are presented that disrupt those generalized views of commerciality — there is more uncertainty than clarity around whether specific uses of online content are commercial or noncommercial.

The families of accident victims start out at a disadvantage when dealing with insurance companies, and when the expenses and hardship of a death are involved, uncertainty concerning a legal case is not easy to handle.

His order removed uncertainty and provided the media with mandatory guidance as to how to involve any risk of being in contempt of court, but it went beyond the powers conferred by s 11.

With every comfort comes the relevant uncertainty of facing a contingency which would involve a financial loss.

Midtown renters insurance adds a little more security to the common uncertainties that are involved with leasing apartments in Milwaukee and elsewhere.