Sentences with phrase «uncharacterized protein»

Structural genomics analysis of uncharacterized protein families overrepresented in human gut...

Gilmore recalls having the «Wow» moment while looking at the sequences rather than the physical protein: «When we got the sequence back, the first thing I did was to sort by size, and at the top you could see a large, uncharacterized protein.

Integrative bioinformatics for functional annotation of uncharacterized proteins and target discovery

We build detailed 3D atomic models of the uncharacterized proteins and their complexes to derive hypotheses that, in close collaboration with the experimentalists, help to predict and understand their function and networks.

This initial project focused on 50 uncharacterized proteins that, based on literature searches, showed some likelihood of being associated with human disease.

Drawing conclusions from this large number of proteins analyzed we have put forward a scheme for systematic localization of uncharacterized proteins, pointing at potential pitfalls of each method and when and how you need to complement the methods or use other methods», says Emma Lundberg.

Not exact matches

1) This study reveals a previously uncharacterized role for RNA in beebread / pollen instead of protein, sugar and hormone in royal jelly to influence caste differentiation.

Here, we identified a previously uncharacterized mammalian - specific protein, Beclin 2, which, like Beclin 1, functions in autophagy and interacts with class III PI3K complex components and Bcl - 2.

However, the secretion systems» proteins and, in particular, their host targets are largely uncharacterized.

«A huge fraction of the human «proteome» remains uncharacterized, and this paper shows how chemical approaches can be used to uncover proteins of a given functionality that have eluded classification based on sequence or predicted structure,» said co-senior author Benjamin F. Cravatt, chair of TSRI's Department of Chemical Physiology.

The experiments identified a previously uncharacterized gene as essential for intoxication by diphtheria toxin and exotoxin A toxicity, and a cell surface protein needed for cytolethal distending toxin toxicity.

In a recent paper in the Journal of Biological Chemistry, Franziska Dierck of the University Medical Center of Schleswig - Holstein and colleagues write that they identified a previously uncharacterized z - disc protein named CEFIP upregulated in cardiomyopathy.