Sentences with phrase «unchecked cell»

Because untimely DNA replication can lead to unchecked cell division, these findings are crucial to a molecular understanding of cancer, a condition marked by runaway DNA replication.

LA JOLLA, CA — A tightly controlled system of checks and balances ensures that a powerful tumor suppressor called p53 keeps a tight lid on unchecked cell growth but doesn't wreak havoc in healthy cells.

LA JOLLA, CA — A tightly controlled system of checks and balances ensures that a powerful tumor suppressor called p53 keeps a tight lid on unchecked cell growth but doesn't wreak havoc...

As a cancer drug, BEZ235 works by inhibiting the PI3K and mTOR metabolic pathways, which help fuel the unchecked cell division that is a hallmark of cancer.

Not exact matches

If left unchecked, however, the inflammatory process churns out toxic substances that can kill surrounding cells, whose death triggers more inflammation and creates a vicious cycle.

As a result, the malfunctioning protein builds up in cells unchecked and keeps the remaining healthy p53 from doing its job.

But 30 had poorly functioning T - regs that let T helper cells proliferate unchecked.

Mutant forms of Lgl allow cancerous cells to reproduce unchecked.

For the most part, stem cell clinics and their claims are unchecked.

Picturing these invisible, single - celled organisms wreaking havoc in the body, unchecked by our best medicines, gives me goose bumps.

In this condition, the stem cells are hyperactive and their division is unchecked,» describes Oostendorp.

According to Munsey Wheby, president of the American College of Physicians, excess fat deposited in the liver is thought to trigger the production of inflammatory molecules that damage cells and ultimately — if left unchecked — lead to cirrhosis.

Because diseases such as cancer tend to evade detection by T - cells» receptors, allowing a tumor to grow unchecked, scientists have long sought «intel» on this process as a means of developing therapies that target malignant cells, but leave healthy cells alone.

This «friendly fire» goes unchecked due to the failing of another type of immune cell: called the T - reg, which controls T - effector cells, shutting them down when they are not needed.

«This is definitely not to say that it will promote tumors,» he says, but the researchers «will have to continue to convince the scientific community that the cells will not divide unchecked the way they do in tumors.»

Another proto - oncogene, Myc normally helps healthy cell division, but can become an oncogene if damaged, causing cells to divide unchecked.

Left unchecked, such mutations would quickly add up, producing cells riddled with genetic errors — a recipe for DNA - damage linked disorders such as cancer, aging and neurodegenerative diseases.

Later, her group reported that cancer cells injected into mice lacking Nr4a1 (therefore lacking patrolling monocytes) underwent unchecked metastasis, supporting the idea that patrolling monocytes play anti-cancer roles.

Unchecked, these free radicals cause a chain reaction of injury to the cells and tissues and, on the skin, results in sun damage, pigmentation and premature ageing.

These protective nutrients neutralize free radicals, which if left unchecked go on to damage cells in the body, including the cells in your blood vessels (12, 13).

As a result, unchecked brain inflammation damages and destroys healthy brain cells.

And cancer basically is cell growth kind of unchecked, right?

As we age, rogue cells, both human and foreign, can proliferate throughout the body unchecked and this damaged tissue can contribute to progressive disease.

A concussion can result in unchecked inflammation that slows recovery and continues to destroy healthy brain cells long after the concussion.

Left unchecked, free radicals can cause damage to cells in the testicles, reducing testosterone production.

Online dating services usually provide unchecked matchmaking over the Internet, through the use of personal computers or cell phones.

These happen to be the wrong cells in the wrong place that do people harm, but this often fatal affliction is based on the idea of propagation, of unchecked growth that can be harmful to the host body.

Left unchecked, free radicals can cause damage to body cells that can lead to chronic or life - threatening diseases such as arthritis and some forms of cancer.

Left unchecked, free radicals react with pretty much any particles they come into contact with — and, when they exist in your hamster's body, those particles are pieces of body cells.

As these cells multiply unchecked, they form tumors.

Responsible for gastroenteritis, pneumonia, skin infections, urinary tract problems, and a host of other diseases, these tiny, one - celled organisms can multiply unchecked in your pet's body without the intervention of antibiotics.

But the upside is three-fold: (i) your tax reduction or dividend check will offset much, perhaps more than 100 %, of those price increases; (ii) you'll be able to minimize your tax bite by cutting down on fuel usage (e.g., shortening those country drives, buying locally - grown produce, purchasing «green power» from wind and solar cells); and (iii) Americans» combined behavior changes in response to the carbon tax will go a long way toward protecting the climate and averting the cataclysmic consequences of unchecked global warming.