Sentences with phrase «uncontrolled cell»

A brain tumor is any intracranial tumor created by abnormal and uncontrolled cell division, normally either found in the brain itself, in the cranial nerves, in the brain envelopes (meninges), skull, or pituitary and pineal gland.

In dogs uncontrolled cell growth or tumors (neoplasia) is not common.

This condition is often associated with dental disease, skin infections and uncontrolled cell growth called neoplasia.

Lung cancer is a disease characterized by uncontrolled cell growth in tissues of the lung.

While there are several different forms of cancer, they are all characterized by uncontrolled cell growth that typically forms a lump or tumor.

This protects the cells from damage and limits uncontrolled cell proliferation, a feature of cancer.

Cancer information and prevention with ellagic acid Cancer: a malignant neoplastic disease -(any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream).

Cancer is said to be a disease of old age, that is because we are living longer, we are encountering more carcinogens which further mutate our DNA which can lead to uncontrolled cell growth.

It's also a case of uncontrolled cell migration.

Not only is cancer riddled with uncontrolled cell growth.

The adenomatous polyposis coli (APC) gene is a tumour suppressor gene, i.e. a gene preventing uncontrolled cell growth that could lead to the formation of a cancer tumour.

Oncogenes — whose protein products, when activated, cause uncontrolled cell proliferation or prevent cells from undergoing apoptosis.

Extensive recombinations usually cause cell death; but subtle translocations involving MLL can result in the rapid, uncontrolled cell division seen in leukemia.

The model will describe cellular pathways that contribute to tumor formation and explain in detail how the genetic disposition of an individual can activate expression of genes that drive uncontrolled cell growth and lead to cancer.

In cancer, mutations occur in a cell's DNA sequence that alter gene expression and cause uncontrolled cell growth.

The glands lining the inner wall of the colon are the sites for most abnormal cell behavior such as uncontrolled cell growth, which results in polyps (non-cancerous growths) and later on in adenocarcinomas or tumors.

Both cases yield the same result — uncontrolled movement of the vehicle or, in the case of cancer, uncontrolled cell proliferation.

All cancers harbour multiple mutations that cause uncontrolled cell proliferation.

Thus the search is on is to discover additional cancer - causing genes «downstream» of TET mutations that drive uncontrolled cell division in either context.

Head and neck cancers are a group of diseases involved abnormal, uncontrolled cell growth in head and neck tissues.

In 1972, she identified a genetic glitch in chronic myelogenous leukemia cells — a swap of genes she called chromosomal translocation — that resulted in the uncontrolled cell growth of cancer.

Like most machinery, the mitotic spindle can malfunction, and when it does, DNA can be broken or unevenly divided, errors implicated in the uncontrolled cell division of cancer.

This indicated that these particular microRNAs could exacerbate uncontrolled cell growth and might be somehow involved in immune system cancers.

Kinesin - 5 has been identified as a target for drugs to treat cancers that involve uncontrolled cell division, such as colorectal cancer, Al - Bassam said.

Failure of this regulation not only impairs the process of development, but also contributes to the reversal of cell differentiation and the uncontrolled cell growth that are the hallmarks of cancer.

But in some cancers — prostate, pancreatic, ovarian and lung in particular — the hedgehogs somehow turn back on, and force uncontrolled cell growth: cancer.

Cancer is caused by uncontrolled cell division, so these effects could explain the disputed leukaemia findings.

The activation of the YAP protein induces uncontrolled cell growth and inhibits cell death, causing malignancies.

Certain skin - dwelling microbes may be anticancer superheroes, reining in uncontrolled cell growth.

The team at the Institute, supported by GSK and together with AstraZeneca have identified another way that PTEN may prevent uncontrolled cell growth.

Not exact matches

This leads to uncontrolled growth of the cells.

Small populations of adult stem cells with somewhat limited developmental potential are responsible for the body's ability to heal injuries and replace worn out cells and tissues, and evidence is growing that rare cancer stem cells are responsible for the uncontrolled growth of some malignant tumors, including glioblastoma.

Uncontrolled growth of these cells leads to anemia, bone pain, kidney problems, Gaucher disease, and myeloma.

«Too little FAM134B leads to an uncontrolled dilation and expansion of this organelle, which is harmful for the cell,» explains Ivan Dikic.

The principle is based on an enzyme, tryptase, that has epigenetic effects that cause cells to proliferate in an uncontrolled manner.

«Cells that lack tryptase start to proliferate in an uncontrolled fashion and lose their identity.

Antibodies derived from a type of immune cell found in unusually high numbers in HIV - infected individuals with chronically uncontrolled virus levels are less effective at neutralizing HIV than antibodies derived from a different type of immune cell more common in people without HIV, scientists report.

To better understand how this abnormal distribution of B cell types in people with uncontrolled HIV affected their immune response to the virus, researchers compared HIV - specific antibodies derived from both TLM and RM B cells.

But University of Wisconsin — Madison researchers reported in May that the virus has the ability to take over a cell's braking mechanism and cause uncontrolled reproduction.

«Antibodies from unconventional B cells less likely to neutralize HIV: Immune cells adapt inefficiently in patients with uncontrolled HIV.»

The researchers believe this difference in B cell distribution among those with uncontrolled HIV adds to a list of reasons most people do not make effective antibodies against the virus.

Myc acts somewhat like a master switch within cells to foster uncontrolled growth.

Like other cancer cells, DLBCL thrive on sugar in the body, drawing on it as as a source of energy it uses to divide in an uncontrolled and almost unlimited manner.

Excessive or uncontrolled inflammation can actually make injuries worse and contribute to disease in a couple of different ways — by activating cell death processes, clogging and rupturing blood vessels and producing toxic molecules like free radicals.

Several factors newly discovered to be phosphorylated by GSK - 3 are also known to be mutated in acute myeloid leukemia, a condition in which aberrant splicing causes uncontrolled white blood cell proliferation.

The more often cells divide, the greater the risk that a genetic mishap will occur that could lead to the uncontrolled proliferation of malignant disease.

Abnormal and uncontrolled production of this class of proteins, known as transcription factors, allow for cells to bypass growth control mechanisms and to develop characteristics necessary for invading surrounding tissues.

Although telomerase could somehow slow aging, it is also found in most tumor cells, where it aids the uncontrolled growth that characterizes cancer.

«Based on our findings, we propose that timely and efficient therapies that target MAIT cells will likely benefit the patients by preventing uncontrolled inflammation and also by relieving immunosuppression,» said Haeryfar.

The telomerase deficiency of human somatic cells reduces the risk of cancer development, as telomerase fuels uncontrolled cancer cell growth.