Sentences with phrase «under hypoxic»

In 1924, the Nobel Laureate Otto Heinrich Warburg, determined that cancer cells have a dependency on glucose for growth and metastastic processes under hypoxic (low oxygen conditions), using glycolysis

Under hypoxic conditions activates the transcription of over 40 genes, including, erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia.

In addition, temporal [17] and spatial [16,17] correlations between increased levels of HIF - 1α, the regulatory subunit of HIF - 1, and increased VEGF expression have been shown, indicating that HIF - 1 may control the expression of VEGF in the retina under hypoxic conditions.

Interestingly, Rho kinase inhibition under hypoxic conditions produced a more effective increase in chondrocyte - specific gene expression and synthesis of extracellular matrix components by HCS - 2 / 8 cells.

Under the hypoxic conditions, the body might produce more reactive oxygen species (ROS), harmful compounds that can damage DNA.

And it is under these hypoxic conditions that the new switch becomes activated.

Not exact matches

Current studies include the exploration of Arctic deep - sea life under the ice, and the long - term observation of the effects of global warming on polar ecosystems as well as on hypoxic aquatic ecosystems.

Higher CH4 emission is likely explained by a higher supply of organic matter under more hypoxic conditions, where CH4 oxidation is less likely to occur.