Publishing online this week in Cell Host & Microbe, researchers at Johns Hopkins report the discovery of a key
underlying immune mechanism that explains why to how our skin becomes inflamed from conditions such as atopic dermatitis, more commonly known as eczema.
Not exact matches
We're just now starting to discover how taste receptors in the upper respiratory tract are used to regulate the
immune system against these infections, so defining the
underlying mechanisms at play is critical to understanding these illnesses and developing new treatments.»
The
underlying mechanism involves the activation of the
immune system, resulting in local inflammation and proliferation of skin cells.
This study is also the first to identify
mechanisms by which gut bacteria triggers changes in the
immune system that
underlie MS progression.
As for the
underlying mechanism, there's evidence that a bacterial protein called endotoxin is important for damping down overactive
immune systems.
She is investigating the role of glycosylated molecules in tumor progression and metastasis, tissue - and species - specific expression of lectin receptors that play a role in regulating host innate
immune responses and inflammation, and the immunological
mechanisms underlying chronic inflammation and cancer development.
The discovery of this «
immune system paralysis» and its
underlying mechanisms represents an important step on the path to improving the treatment of spinal cord injury patients.
«Although the
underlying mechanism leading to this increase in AMD in persons with AIDS is not yet known, it may relate to the state of chronic
immune activation and systemic inflammation seen in these patients,» said Dr. Jabs.
«Knowing this
mechanism that
underlies IL - 37's effect on the
immune system now allows us to study IL - 37 function and perhaps dysfunction in a wide range of diseases,» says Mayumi Fujita, MD, PhD, investigator at the University of Colorado Cancer Center, associate professor in the CU School of Medicine Department of Dermatology, and the paper's senior author.
Her work seeks to elucidate the
mechanisms and pathways
underlying the interaction between the
immune system and cancer using mouse models that recapitulate the coevolution of tumor progression and the antitumor
immune response.
The
mechanism which
underlies the susceptibility of liver disease patients to life - threatening infection has been uncovered by Wellcome Trust - funded medical scientists, who have also suggested a possible treatment to reverse
immune suppression in these patients.
In addition, the study investigated whether Hyssopus officinalis L. was able to increase
immune reactions and thus, may be used to improve and perfect the
mechanisms underlying the treatment of asthma.
This workshop will discuss new approaches to quantifying
immune cell function as well as the metabolic
mechanisms that
underlie this function.
The success of
immune checkpoint inhibitors in cancer therapy continues to grow, but a complete understanding of their
underlying mechanisms is still lacking.
Because double - stranded viral RNA is typically longer than that naturally found in cells, Hur surmised that a
mechanism that uses length to distinguish between viral and cellular RNA might
underlie the
immune system's discriminatory power.
Instead of masking symptoms, functional medicine is concerned with the
underlying mechanisms that give rise to health problems like a weak
immune system.
Although thyroid medications may be necessary, they do not address the
underlying mechanism of Hashimoto's hypothyroidism, which is an autoimmune reaction and
immune imbalance.
Endothelial cell activation, vascular smooth muscle dysfunction, oxidative stress, and inflammation,
mechanisms which
underlie heart disease, diabetes, and hypertension, are all variables which can precipitate or perpetuate
immune imbalances in autoimmune disease.
A constantly triggered
immune response provokes a cascade in stress responses and is the fundamental
mechanism underlying most imbalance and illness.
Mechanisms underlying these effects may include free - radical scavenging effects,
immune system modulation, brain neurotransmitter modulation, and hormonal effects.
Because cats normally have very concentrated urine and effective
immune mechanisms, it is very rare for them to have a bladder infection unless there are
underlying conditions that allow bacteria to grow.