Current projects include modeling the biophysical mechanisms
underlying synaptic plasticity and learning in dendritic trees, the dynamics of neuronal networks in the outer plexiform layer of the retina, and modeling the integration of multiple synaptic inputs in muscle fiber.
Since morphology changes of synapses
underlie synaptic plasticity and our learning and memory, this will provide us with many new insights into mechanisms of how neurons store information in their morphology, how it changes synaptic strength and ultimately how it creates new memory.
Not exact matches
They used a somewhat bizarre technique in which two mice were sutured together in such as way that they shared a circulatory system (known as parabiosis), and found old mice joined to their youthful counterparts showed changes in gene activity in a brain region called the hippocampus as well as increased neural connections and enhanced «
synaptic plasticity» — a mechanism believed to
underlie learning and memory in which the strength of neural connections change in response to experience.
Using these techniques, Dr. Watanabe is studying cellular and molecular mechanisms
underlying synaptic transmission and
synaptic plasticity.
Professor Martin's research focuses on the cell biology of transcription - dependent forms of
synaptic plasticity, particularly those
underlying learning and memory.
Researchers have discovered a new form of
synaptic plasticity, the changes to nerve cells in the brain that
underlie learning and memory.
Using these approaches in combination with genetics, molecular biology and biochemistry, we are studying the molecular mechanisms
underlying synaptic transmission and
plasticity in mammalian central nervous system.
«We hope to gain a comprehensive understanding of the connectivity and
synaptic plasticity mechanisms
underlying higher brain functions,» says neuroscientist Kyungjin Kim, president of the Korea Brain Research Institute.
Increased perfusion to brain tissue, decreased body weight, upregulation of growth factors and improved
synaptic plasticity may all be molecular mechanisms
underlying the benefits of enrichment and activity therapies.