Sentences with phrase «understand axonal»

Our second major line of research aims to understand axonal pathology in SMA, an autosomal recessive neuromuscular disease.

Richard T. Libby, PhD University of Rochester Medical School, Rochester, NY Funded by The Alcon Foundation Project: Understanding Axonal Degeneration Pathways in Glaucoma

Not exact matches

Hayashi and Niwa expect the non-invasive force measurement method to be a strong, new tool in understanding the physical mechanism of neuronal diseases caused by deficits in axonal transport.

This suggests that understanding the role of dysregulated miRNA in mDA neurons may provide insights into the pathophysiological mechanisms of mDA axonal degeneration in PD, and provide new opportunities for mDA axonal protection or re-growth.

Therefore understanding the dysfunctional molecular pathways that cause mDA axonal degeneration, and targeting these to protect or re-grow mDA axons, may be a promising therapeutic approach for PD.

Dominant mutations in the MORC2 gene have recently been shown to cause axonal Charcot - Marie - Tooth (CMT) disease, but the cellular function of MORC2 is poorly understood.