Sentences with phrase «understand cellular organization»
Not exact matches
Her research is at the interface between bioimaging and proteomics, and aims to define the spatiotemporal organization of the human proteome at a subcellular level in an effort to understand how variations and deviations in localization contribute to cellular function as well as disease.
http://www.sciencemag.org/
The goal of the NIH program, as described on its website, is «to understand the principles behind the three - dimensional organization of the nucleus in space and time (the fourth dimension), the role nuclear organization plays in gene expression and cellular function, and how changes in the nuclear organization affect normal development as well as various diseases.»
Their observation provides a better understanding of cytoskeletal self - organization in general, which may in turn lead to better drug design and new materials that can mimic cellular behaviors.
The answer to this daunting biological riddle is central to understanding how the three - dimensional organization of DNA in the nucleus influences our biology, from how our genome orchestrates our cellular activity to how genes are passed from parents to children.
To understand the whole cellular organization, it is necessary to identify, quantify and characterize proteins and their relationships within functional networks, which is affordable by combining efficient separation strategies and bioanalytical methods showing a high resolving power, accuracy and sensitivity.