he continues to pose questions and do experiments that affect our ability to
understand the human genome... and he continues to change the way we think about the genome, how to navigate it, and what those changes mean in transcriptional regulation,» said Elaine A. Ostrander, NIH Distinguished Investigator and Chief of the Cancer Genetics & Comparative Genomics Branch at the National Human Genome Research Institute and one of those nominating Kruglyak for this honor.
«By means of basic research on model organisms, we are trying to
understand human genome instability to identify elements, which, in the future, might be able to be explored as targets of new anti-tumour medicines,» explains the researcher responsible for the project and director of Cabimer, Andrés Aguilera.
«If we can improve our ability to read and
understand the human genome, we will also be able to make better use of the rapidly accumulating genomic information on a large number of diseases for medical benefits.»
She quoted Nancy Edwards, a professor at Harvard Medical School (8): «If we have the audacity to believe that we can find cures for cancer and
understand the human genome, why should it be hard to believe that we can fix the culture of our profession?»
Headquartered in Reykjavik, Iceland, deCODE is a global leader in analyzing and
understanding the human genome.
Headquartered in Reykjavik, Iceland, deCODE genetics is a global leader in analyzing and
understanding the human genome.
The mouse genome is essentially a reference manual for
understanding the human genome.
About deCODE deCODE is a global leader in analysing and
understanding the human genome.
Findings Published in New England Journal of Medicine Provide New Focus for Drug Discovery Study Demonstrates Power of «Big Data» Research REYKJAVIK, Iceland - deCODE Genetics and Illumina, global leaders in analyzing and
understanding the human genome, together with...
We have made amazing strides in recent years in
understanding the human genome.
Not exact matches
Then, given your clearly profound
understanding of the relevant science, you can explain how
humans came to possess a defunct gene for egg - yolk proteins in our placental mammal
genomes and why the presence of this dead gene and the mutations rendering it defunct map to the lineages observable in the fossil record?
There is a vast difference between mapping the
human genome, and
understanding all that it contains.
You doubt something like carbon dating, without realizing how old isotope knowledge is, nor do you
understand how far beyond we are in
human genome research.
Even though we knowtoday that species occur rapidly following a ass extinction, the opposite of Nye's
understanding of science, there remains the oxymoron of rapid, or random mutation evolution Dr. Gould's work in the area of random mutation evolution was very popular until the
human genome project proved that Dog is Man's closest
genome relatve.
The concept of race (based on phenotype — such as the amount of melanin in the skin — this is what Chad means when he uses the word) has largely been discredited and discarded due to our recent
understanding of the
human genome.
But it is a use — the most likely use, at present — of advancing
understanding of the
human genome.
«Our future in medicine and in health depends on
understanding the information contained in the
human genome, so it's a great topic for Science Week,» said Dr. Norma J. Nowak, Director of Science and Technology at UB's New York State Center of Excellence in Bioinformatics and Life Sciences.
One way scientists can
understand the genetics of domestication is to look at what parts of the
genome are altered in response to living together with
humans, Warren added.
So when President Obama announced an ambitious plan to
understand the brain in April 2013, people were quick to view it as the next Manhattan Project, or
Human Genome Project, or moon shot.
The group also compared the cat
genome with those of other mammals — including a tiger, cow, dog and
human — to
understand more about the genetics of cat biology.
We want to
understand the basic mechanism underlying these multiple new copy number variant mutations in the
human genome.»
Although researchers do not yet know the biological significance of these discoveries, they say that fully cataloguing the
genome may help them
understand how genetic variations affect the risk of contracting diseases such as cancer as well as how
humans grow from a single - celled embryo into an adult.
«This study shows us how far we are from a comprehensive
understanding of the
human genome.»
Along the way, the hope is that the project will transform the technology of neuroscience — in the same way that the
Human Genome Project (HGP) helped take genome - sequencing from pipe dream to everyday reality — and ultimately revolutionise our understanding of brain fun
Genome Project (HGP) helped take
genome - sequencing from pipe dream to everyday reality — and ultimately revolutionise our understanding of brain fun
genome - sequencing from pipe dream to everyday reality — and ultimately revolutionise our
understanding of brain function.
«Once we can build that sort of database for the
human organism, it helps us much better
understand disease, how to diagnose disease, how better to treat disease,» says Richard Wilson, the director of the
Genome Sequencing Center at Washington University in St. Louis.
Ausiello likens the ventures to the
Human Genome Project — but instead of
understanding the vast library of our genes, CATCH and Google are building a library of the behaviours and environments that can prevent or cause disease.
«
Understanding this previously ignored part of the
human genome, its role in
human development, and how it may be taken over by disease, opens a new frontier in science with important implications for medical advances,» said Philipp Kapranov, Ph.D., lead researcher at the St. Laurent Institute.
The findings, published in the journal Nature, explain why the
human genome is so difficult to decipher — and contribute to the further
understanding of how genetic differences affect the risk of developing diseases on an individual level.
«Having this complete set of instructions gets us one step closer to
understanding how a free organism functions,» points out Francis Collins, director of the National
Human Genome Research Institute (NHGRI) in Bethesda, Maryland.
The
human genome project, ambitious as it was, has turned out to be only the start of the quest to
understand the molecular blueprint for life.
... The projects that are ongoing, like the
Human Cancer
Genome Project, [have] really opened up a lot of possibilities to
understand the molecular basis of cancer.
So our focus will be to study the
genome through the transcripts in biological systems, to
understand the genetic architecture of Pan-Asian populations, and finally to focus on the intersect between genomics and
human medicine.
Sudmant, a UW graduate student in
genome sciences, said, «Gathering this data is critical to
understanding differences between great ape species, and separating aspects of the genetic code that distinguish
humans from other primates.»
«Here it is the 10th anniversary of the
human genome, and I have PhD students in my lab who say «I can't
understand how an old man like you possibly worked on this stuff before the
genome was decoded.
The
human genome is coming out right now, and that is a resource that we'll only
understand by using bioinformatics.
«Now that we have a better
understanding of how an animal is built we can get some way closer to knowing how the
human body works in health and disease,» says John Sulston, director of the Sanger Centre at the Wellcome Trust
Genome Campus, Cambridgeshire, England.
«It's essential to have all of the great ape
genomes in order to
understand the features of our own
genome that make
humans unique,» says Gregory Wray, an evolutionary biologist at Duke University in Durham, North Carolina, who was not involved in the study.
The study, led by Dr. Maximilian Muenke of the National
Human Genome Research Institute in Bethesda, Maryland, brings scientists closer to
understanding how ADGRL3 contributes to risk by providing functional evidence that implicates a transcription factor in the pathology of the disorder.
«NGS technologies have vastly improved our
understanding of the
human genome and its variation in diseases such as cancer,» said Ken Chen, Ph.D., assistant professor of Bioinformatics and Computational Biology and co-author of the Nature Methods article.
«Though the degree to which
human embryonic stem cells possess this feature is not entirely clear, by
understanding how another complex organism's
genome works we ultimately learn more about how our own
genome works,» said Zhou.
That is how he became more famous for deciphering the
human genome than the international army of scientists who shared the achievement, how he hopes to
understand every microbe in the ocean (through his Global Ocean Sampling Expedition), and how he plans to create artificial life.
«For 15 years, an impressive amount of time and money poured into discovering the
genomes of mammals, motivated by our drive to
understand human evolution and to look for cures for disease.
Building on years of mouse and gene regulation studies, they have developed a resource that can help scientists better
understand how similarities and differences between mice and
humans are written in their
genomes.
«This was a bit of a surprise and something I wish we
understood a little better,» says Francis Collins, one of the discoverers of the CF gene and head of the US National Center for
Human Genome Research.
To better
understand these biases, laboratories can now compare their DNA sequences to those obtained from the DNA in any or all of the
human genome RMs.
Until scientists
understand more of the landscape of the
human genome, she says, she will have a hard time believing that adaptive genetic differences between ethnic groups have mushroomed over the past 20,000 years.
Like many others, he believes that GWAS have had a major impact on our
understanding of the
human genome, and he plans to send comments to Cell.
Haplotype - resolved information for the
human genome is essential for
understanding the relationship between genotype and phenotype.
The work on gorilla and other
human genomes clearly demonstrates that large swathes of genetic variation can't be
understood with the short sequence - read approaches.
More recently, scientists have identified parts of the
human genome carrying Neandertal genetic variants, but — in part because Neandertal - derived DNA is so hard to identify and also because of the expense of performing tests for its influence on individuals — scientists still don't fully
understand how Neandertal - derived variants influence modern
human traits.