Sentences with phrase «understand immune responses to cancer»
Not exact matches
«This research represents a big step forward in understanding why some tumors are more aggressive than others and being able to predict rationally which neoantigens will be the most effective at stimulating an immune response,» said Dr. Balachandran, a member of the David M. Rubenstein Center for Pancreatic Cancer Research at MSK, and corresponding author of the companion study in Nature.
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That study showed how a similar model can be used to understand immune response in patients with pancreatic cancer who survive longer than others.
In addition to formulating diagnostic strategies for cancer immunotherapy agents, her team is focused on developing a deep understanding of tumor immune biology as well as mechanisms associated with immune response and immune escape in cancer patients, with the intent of generating rational strategies for the creation of combination therapies.
Immuno - oncology is a rapidly growing field of cancer treatment based on understanding the body's immune response to cancer.
For understanding the biology of gene - gene, gene - drug and gene - microenvironment interactions, a considerably broader range of in vitro and in vivo model systems is required — we are generating 1,000 organoid cultures from human cancers, characterising their genomes, functional dependencies and drug response, and we are expanding our in vivo models to study the interface between cancer and the immune system and microenvironment.
The work will be an important step towards understanding how immune function is controlled during immune responses to infection and cancer.
Over the past few years, they have extended their research to understand how products of cellular necrosis and the innate immune responses they induce affect the tumor microenvironment, with a specific focus on ovarian cancer.
As a surgeon who treats patients with head and neck cancer, Kim approaches research from a translational standpoint to understand the relationship between neoplastic transformation and the host immune response.
Fortunately, he said, there have been advances in understanding the relationship between the immune system and breast cancer and the difference between subtypes and their response to immunotherapy.
The focus of my research is on understanding how cancer impacts host immune responses in patients, with the goal of developing novel treatments to restore / enhance immune function in cancer patients.