Sentences with phrase «understand normal protein»

CRISPR has allowed scientists to tag and light up endogenous genes of interest to better understand normal protein function.

Not exact matches

Allan Jacobson, Ph.D., of the University of Massachusetts Medical School and co-founder of PTC Therapeutics, the company that developed ataluren, and David Bedwell, Ph.D., professor of the UAB Department of Biochemistry and Molecular Genetics, have sought to understand precisely how ataluren allows the ribosome, the machinery of cellular protein synthesis, to skip over these inserted stop signs and produce proteins that have normal or near - normal function.

He says it's also important to understand the protein's biological role in cellular signaling and normal animal development as well as to consolidate its role in human cancer development, progression and drug - resistance.

Detecting protein - protein interactions is key to understanding both normal and abnormal functions in the cell.

«In general, scientists try to understand disease - causing mutations in the context of all the studies we've done on the normal protein,» Shokat said.

The normal role of Ro was not well understood although it was known that the protein is normally found bound to small RNA molecules called Y RNAs, whose function remains somewhat mysterious.

A better understanding of the normal role of the huntingtin protein would make developing treatments easier.

Understanding the normal function of this essential protein is vital to understanding the root of the disease, yet despite more than a decade of investigation, its role in the cell remUnderstanding the normal function of this essential protein is vital to understanding the root of the disease, yet despite more than a decade of investigation, its role in the cell remunderstanding the root of the disease, yet despite more than a decade of investigation, its role in the cell remains elusive.

The more we understand about how the normal and extra-long huntingtin proteins are made and work in brain cells, the better equipped we'll be in the search for HD treatments.

Several gene rearrangements have been engineered and their protein products have been expressed in both normal cells and cancer cells to understand the effects of each rearrangement on cell function and targeted drug effectiveness.

While it does not address the quantity problem that you raise, it is important information for someone who is concerned about protein: http://nutritionfacts.org/topics/protein/ My understanding is that too much protein (even the amount most normal Americans eat, not to mention the amounts your body builder is promoting) is bad for the kidneys.

However, it is my understanding that normal traditional soy foods like tofu, soymilk, and tempeh contain NO soy protein isolate.

I have been led to understand that if her metabolic functions and enzymes are not normal she may not be absorbing the needed vitamins, proteins and fat that a dog needs for proper health.