Sentences with phrase «understand vaccine response»

«There is a critical public health need to translate these findings to humans and understand vaccine response in this growing segment of the population,» Schultz - Cherry said.

Not exact matches

«The emergence of Zika virus has further complicated vaccine design, and emphasizes the need to better understand the molecular mechanisms that underpin protective antibody responses.»

«Understanding the host response will be a critical area in vaccine research,» says George Kemble, vice president of research and development for MedImmune Vaccines, recently purchased by AstraZeneca.

Understanding the body's immune response to a given vaccine could help make better and more effective vaccines in the future.

Equipped with this deeper understanding, researchers are trying to make allergy vaccines safer and more effective by designing them to micromanage the allergic immune response.

Vaccine immunology is poorly understood in pregnancy and Tfh cell expansion has been shown to be a predictor of response to influenza vaccination outside of pregnancy.

The cholera studies led to the scuttling of a leading vaccine candidate, a finer understanding of effective immune responses, and, ultimately, compelling evidence that a different cholera vaccine worked.

«Nonetheless, we are pursuing a deeper understanding of this process to see if it is involved in producing adequate antibodies in response to vaccines.»

Significant advances also have been made in understanding T - cell responses that may be important to vaccine - induced immunity against HIV.

We assess spontaneous and vaccine - induced immune responses against melanoma, and have a particular interest in developing methods for understanding functional subpopulations within melanoma and the optimal ways of targeting them therapeutically.

It is critical to understand how best to design a cancer vaccine such that it recognizes only the tumor without inducing an equally destructive autoimmune response to normal issue.

As such, genomic research is improving our understanding of infectious disease pathogenesis and immune response and may help guide future vaccine development and treatment strategies [11][18].

The P5 aims to produce an HIV vaccine that could have a significant public health benefit in southern Africa and to deepen scientists» understanding of the immune responses associated with preventing HIV infection.

Career Goals: I plan to pursue a career in scientific research focused on understanding the human immune response to various infectious agents for diagnostic and vaccine design purpose.

Research Focus: My research project focuses on the T cell response of mycobacterium tuberculosis to further understand how the current BCG vaccine can be improved.

I am interested in understanding how dengue virus and zika virus - specific T - cell responses can mediate protective immunity or disease pathogenesis, and in defining new protective T - cell epitopes for immunotherapeutic reagents or novel vaccine development.

Using gene - targeted mice and human cells that lack specific components of the immune system, a better understanding of the immune response to DENV and ZIKV is critical for developing much - needed vaccines and antivirals.

Immune Design is a new generation vaccine company built on emerging understanding of the role of dendritic cells in determining an effective immune response.