Sentences with phrase «understanding gene expression changes»

This is important, he added, because this technique is increasingly used for classifying diseases and their subtypes, understanding gene expression changes during development and tracking the progression of cancer.

Not exact matches

This study could help us understand how changing messenger molecule tails could control gene expression in the context of regeneration.

The goal of the NIH program, as described on its website, is «to understand the principles behind the three - dimensional organization of the nucleus in space and time (the fourth dimension), the role nuclear organization plays in gene expression and cellular function, and how changes in the nuclear organization affect normal development as well as various diseases.»

For instance, they discovered that ppGpp - mediated effects are the key to understanding constitutive gene expression under environmental changes, including both nutrient and antibiotic changes.

«Understanding which genes are involved in transgenerational acclimation, and how their expression is regulated, will improve our understanding of adaptive responses to rapid environmental change and help identify which species are most at risk from climate change and which species are more tolerant,» Dr VUnderstanding which genes are involved in transgenerational acclimation, and how their expression is regulated, will improve our understanding of adaptive responses to rapid environmental change and help identify which species are most at risk from climate change and which species are more tolerant,» Dr Vunderstanding of adaptive responses to rapid environmental change and help identify which species are most at risk from climate change and which species are more tolerant,» Dr Veilleux says.

This is not a very conceptually satisfying situation and does little to advance our understanding of the mechanism (s) underlying the changes in gene expression in response to the perturbation or its implications for clinical phenotype.

The findings improve our understanding how changes in diet and gene expression affect the speed of aging.

A long - term goal of our research is to understand how neuronal activity elicits changes in gene expression that are important for learning and memory.

The NIH Common Fund's Library of Integrated Network - based Cellular Signatures (LINCS) program aims to create a network - based understanding of biology by cataloging changes in gene expression and other cellular processes that occur when cells are exposed to a variety of perturbing agents.

By determining how changes in gene expression affect the fate of glial cells in mice, we hope to understand the key factors that govern neural cell regeneration in the human brain.

Nick Owens, a post doc in Mike Gilchrist's lab, who developed the computational analysis, said: «This study improves our ability to understand the way gene expression changes with time, and from this we gain insight into the logic of how gene expression is regulated.

Maybe we can integrate our understanding of the many exposures tied to schizophrenia and the many genes tied to schizophrenia with the understanding that certain exposures may act by changing gene expression.»

Although the functional bases for these global changes in B. burgdorferi gene expression are not understood, they are generally considered to constitute an adaptive response that facilitates transition between two distinct niches: the tick and the mammal.

Epigenetics provides another way of understanding how genes and environment interact in that there is increasing evidence that gene expression is moderated by the environment in which the organism grows and develops.15 Genetic information is encoded not just in DNA linear sequences but in epigenetic changes in chromatin structure such as DNA methylation or covalent modifications of the DNA - binding proteins.