The understanding of cell identity, heterogeneity and plasticity in neuroblastoma has strong implications with respect to the development of new therapeutic strategies to eradicate tumor cells in neuroblastoma patients.
Not exact matches
Understanding this process - which is particularly important when
cells are first taking on specialized
identities such as nerve
cells, muscle, skin, and so on - helps explain how complex organisms can arise from a finite number
of genes.
Understanding both aspects
of a stem
cell's
identity could be crucial to generate functional and mature
cell types for regenerative medicine.»
To
understand why skin
cells in diverse parts
of the body have different characteristics - how
cells know their «positional
identities» - a fact that guides the diagnosis and treatment
of many skin diseases, Dr. Chang and his colleagues are seeking to define in molecular terms how the expression
of different genes in stromal
cells determines their ability to affect the development
of skin
cells.
His research with Dr. Kerry Ressler utilizes mouse models
of fear learning to better
understand the molecular
identities of cell populations involved in these learning events.
Scientists have used
cells» visual appearance, or morphology, as a way to help
understand their state and
identity essentially since the invention
of the microscope.
Barton Lab discovers how stem
cells maintain
identity (12/1/16) The Barton lab is leading the way in
understanding the functions
of non-coding RNAs, especially at the convergence
of stem -
cell biology and epigenetics.