This technique has been used, as Arnold reports, to trace the progress of cancers, advance
our understanding of obesity and diabetes, and prove that brain cells continue to form through a human being's lifetime.
Not exact matches
It is highly associated with
obesity and diabetes,
and is one
of the reasons for concern over the increasing rates
of both problems in the U.S. NASH can lead to cirrhosis
and to hepatocellular carcinoma (liver cancer), so
understanding its development is becoming more
and more important.
«This not only advances our
understanding of how the body responds to cold, but could lead to new ways to control the amount
of brown fat in the body, which has links to
obesity,
diabetes and fatty liver disease,» says senior author Ronald Evans, Howard Hughes Medical Institute investigator
and holder
of Salk's March
of Dimes Chair in Molecular
and Developmental Biology.
The major challenge is getting closer to a mechanistic
understanding of why type 2
diabetes and obesity occur
and why they have become so much more common in the last 40 - 50 years.
The new finding contributes to a fuller
understanding of the fundamental biology that underlies common metabolic diseases related to
obesity, such as type 2
diabetes, fatty liver disease,
and heart failure,
and could lead to new insights on how to better treat such diseases.
Understanding the brown fat tissue
and how it can be used to such ends is
of growing interest in the search to help people suffering from
obesity or at a high risk
of developing
diabetes.
Once better
understood, these genetic mechanisms may not only help to explain why not all
of those who are obese develop related metabolic diseases, such as type 2
diabetes and high cholesterol, but could lead to possible ways to treat
obesity or prevent metabolic diseases in those who are already obese.
Dr Wael Kafienah, from the University
of Bristol's School
of Cellular
and Molecular Medicine, explained: «The existence
of obese individuals with lower risk
of diabetes has received great interest in the past few years, as they may hold the clue to
understanding and possibly treating
obesity - associated
diabetes.
«The addition
of osteocalcin as a metabolic regulator may one day lead to novel therapies, but we need to
understand much better how it works
and how it fits into physiology before such therapies can be attempted in humans,» says endocrinologist Mitch Lazar, director
of the Institute for
Diabetes,
Obesity,
and Metabolism at the University
of Pennsylvania.
«Altogether, given the high mortality
of PDAC
and the expected increase in
obesity and diabetes over the next few decades, efforts should be undertaken to mechanistically
understand the link between
obesity,
diabetes,
and PDAC.
What the researchers found using this technique could have significant impact on both the
understanding and treatment
of obesity,
diabetes and cardiovascular disease.
«Moving forward, this more sophisticated
understanding of the relationship between
diabetes and obesity should enable researchers not only to develop therapies targeting these mechanisms, but also to identify the appropriate patients to whom these therapies should be targeted.»
We believe that this new information on the structure
of the adiponectin receptors will help us
understand new relationships between the structure
and functions
of these important receptors, which we know to be evolutionarily conserved,
and hopefully will contribute to the development
of new adiponectin receptor agonists that can be used for the treatment
of obesity - related diseases such as type 2
diabetes.
«Given the growing epidemic
of obesity,
diabetes,
and NAFLD, this study brings to the attention
of policymakers, providers, pharmaceutical companies, payers,
and patients the critical importance
of understanding NAFLD
and establishing a policy for prevention, early detection,
and effective therapy,» said Dr. Younossi.
It is important to
understand pubertal timing as early pubertal onset can influence the risk
of developing a number
of health disorders such as
obesity and diabetes in adulthood.
The Pennington Biomedical Research Center is at the forefront
of medical discovery as it relates to
understanding the triggers
of obesity,
diabetes, cardiovascular disease, cancer
and dementia.
We need to
understand how these adaptations between generations occur since these may help us
understand the record levels
of obesity and type 2
diabetes in our society today.»
• In nutrigenetics, the aim is to
understand how genetic makeup determines response to diet
and susceptibility to diet - related disease — i.e., a number
of genetic variations have been shown to increase the susceptibility to Type 2
diabetes,
obesity, cardiovascular diseases
and some autoimmune diseases
and cancers.
It will also help us to develop a new
understanding of the relationship between high blood pressure
and related conditions such as high cholesterol,
obesity and diabetes, heart attack
and stroke.
Based on Dr. Nelson's fundamental work, particularly in the area
of molecular, cultivation - independent analysis
of the structure
and function
of microbiomes, nowadays researchers
understand the human microbiome as an important factor driving human health
and investigate links between changes in microbiome structures
and diseases like
diabetes or
obesity.
Did I
understand you correctly as saying that LCHF is your preferred method
of treating insulin resistance,
diabetes and obesity based on your opening sentence,» such as the LowCarb HighFat diets that we prefer», that fasting is a secondary option based on the difficulties some people have following or
understanding LCHF except in the extreme cases you mention in # 5 where both may be the best solution?
«Now as we
understand the biochemistry
of the body better, we know that eating too many carbohydrates causes
obesity, as well as
diabetes, insulin resistance,
and many other chronic diseases.»
Currently, his professional focus as a scientist
and professor (Brigham Young University) is to better
understand chronic modern - day diseases, with special emphasis on the origins
and consequences
of obesity and diabetes.
«Further research in cats is warranted to
understand the role
of these fascinating molecules so that therapies for diseases such as
obesity and type - 2
diabetes mellitus can be developed,» she says.
A post-doctoral fellow at the Auburn University College
of Veterinary Medicine, Dr. Graff heads a research project to
understand obesity and diabetes -LSB-...]
we'll provide you with the information you need to getter better
understanding of your dog's daily feeding guidelines as well as tips
and insight in to the common mistakes dog owners make when feeding their pets - which is part
of the reason why so many dogs are now suffering with
obesity and its subsequent by - products such as canine arthritis, canine
diabetes and other such nasty canine conditions.
In my passion to ensure that the world
understands the risks
of cancer,
obesity and diabetes, I have often referred to heart disease, coronary artery disease, as a collateral health issue.
This project will provide relevant findings regarding
understanding of GDM, potential pathways
and its link to lifestyle, mental health
and the development
and trajectories
of obesity and diabetes in the mothers
and obesity in their offspring.