Sentences with phrase «unique preclinical models»

Duke s research will use patented multielectrode technology to directly measure the activity of hundreds of neurons to study brain dynamics in unique preclinical models of diseases such as Parkinson s and schizophrenia.

Not exact matches

This model offers unique capabilities for preclinical assessment of thrombosis risk in a patient - specific manner, including efficacy testing of anti-thrombotic agents, elucidation of mechanism of action, and, potentially, biomarker identification, all providing a much - needed platform for drug discovery and development.

We have recently identified which cells are uniquely responsible for the metastasis formation in OSCC, and they exhibit the following characteristics: i) they are exclusive in their ability to generate metastases; ii) they express the fatty acid translocase CD36, and express a unique lipid metabolic signature; iii) they directly link metastasis predisposition to dietary fat content; iv) they increase their metastatic initiation potency when treated with palmitic acid; v) they are highly sensitive to CD36 inhibition, which almost completely abolishes their metastatic potential in preclinical models (Pascual et al., Nature 2016).

Biomedcode is a Contract Research Organisation (CRO) providing full preclinical drug evaluation services to the pharmaceutical industry using a unique collection of mouse models of human inflammatory diseases.

Overall, SR - Tiget represents a multi-disciplinary research environment, which provides a unique blend of scientific expertise in the development of innovative gene and cell therapy strategies, access to relevant preclinical models to evaluate their efficacy and safety, as well as competence in conducting early phase clinical trials.