Sentences with phrase «unknown human genes»
The consortium researchers discovered about 9,000 previously unknown mouse genes and about 1,200 previously unknown human genes.
http://www.genomenewsnetwork.org/ Not exact matches
DNA phenotyping uses genes from human remains to give police an idea of what an unknown person looked like.
Using a genome - wide genetic screen, Dr. Gelman and colleagues identified a previously unknown metastasis suppressor — the FOXO4 protein, which belongs to a family of genes that are produced by all human cells.
Joint lead author Professor Manfred Kayser from Erasmus MC said: «Besides substantially increasing our understanding of human pigmentation genetics in general, finding these new hair colour genes is also important for further increasing the accuracy of hair colour prediction from DNA traces in future forensic applications, which can help to find unknown perpetrators of crime.»
To find and clone a human gene of unknown function, researchers begin with a genetic map.
«Today, rapidly falling costs means that high throughput sequencing projects are revealing the entire gene sequences of ever more species, but the biological functions of most of these genes remain unknown,» said Dr. Olivier Lichtarge, professor of molecular and human genetics and director of the Computational and Integrative Biomedical Research Center at Baylor and senior author of the report.
«Humans also suffer from different types of inherited chondrodysplasia, and the ITGA10 gene could represent a good candidate gene for some of these disorders, which still have an unknown genetic cause,» tells Kaisa Kyöstilä, the first author of the paper.
A computational tool developed at the University of Utah (U of U) has successfully identified diseases with unknown gene mutations in three separate cases, U of U researchers and their colleagues report in a new study in The American Journal of Human Genetics.
The function of the majority of genes in the mouse and human genomes remains unknown.
After more calculations and more computer modeling, Bohlender and his crew laid out one potential answer: the possibility of a third, unknown human ancestor contributing to the Melanesian gene pool.
The biological function of the vast majority of the > 18,000 human genes remains unknown.
This study identified 1,317 distinct genes found to be knocked out in humans; many of these genes (e.g., APOC3, PLA2G7, LPA) are being pursued as therapeutic targets, whereas many others are novel genes of unknown function.
Adults who had been categorized as behaviorally inhibited at the age of 2 years exhibited a higher amygdala activation in response to unknown vs familiar faces16 compared with adults who were uninhibited as children, consistent with the notion that novel or ambiguous environmental stimuli of potential biological relevance activate the amygdala.17 Turning to genes that can influence the neurobiological bases of the processing of emotions, 2 common alleles, the short (S) and the long (L), in a variable repeat sequence of the serotonin transporter (5 - HTT) promoter polymorphism (5 - HTTLPR) on human chromosome 17q11 have been differently associated with greater amygdala activity in response to angry or fearful faces18 in healthy adults.