Sentences with phrase «unmet need»

The big thing for me is just that there's a huge, unmet need.

In their research, students also delve deeper into understanding their customers» experiences to design for an unmet need by interviewing a user and analyzing user data.

«There a huge unmet need for many adults to come to terms with childhood bereavement.

Instead, they realized that if a kid is acting out, he or she has an unmet need.

A competitor, Hinge, recently rebranded, calling itself «The Relationship App» — which Carbino describes as a «clever marketing stunt» — something that perhaps indicates an unmet need in the market.

Considering the magnitude of the unmet need for effective and non-addictive pain treatments, more work is needed.

Recently pain was highlighted in an overview of neurological disorders that should be considered for metabolic therapy; 21 clearly, treatment of pain and inflammation is a prevalent and unmet need.

During this time he saw the unmet need for something natural that could help his IBS patients find real relief.

At that moment, I analyzed my unspoken, unmet need for holding steady with my weight: flavor variety.

If this sounds like you then you could be using sweets to fill an unmet need for emotional comfort and love.

Food can help distract us when we're going through challenging times, but figuring out the unmet need can provide some lasting relief.

At the same time, it highlights an unmet need for interventions to decrease acute care utilization by residents» patients throughout the academic year.»

«The proposed experiments, if successful, will address an important unmet need in bringing stem cell therapies to clinical use and provide the foundation for a wide range of additional applications,» Clegg said.

Pfizer initiated a Phase 1 clinical study for EOS200271 (NCT02764151) as a single agent in patients with malignant gliomas (brain cancer), an area of significant unmet need, based on brain penetration of the compound.

While there has been meaningful progress in the development of therapeutics that address the underlying SMA genetic defect, there continues to be a high unmet need for therapeutics that directly address muscle atrophy.

This is an area of unmet need where cancer investigators and providers require guidance as to the implications of those variants for cancer care.

Soft Tissue Sarcoma Opportunity: in both our monotherapy single arm Phase 1 and combination randomized Phase 2 studies, we are focusing on two types of sarcoma where we believe there is significant unmet need: synovial sarcoma and Myxoid round cell liposarcoma.

The NIH should increase its funding for fruit fly research, the authors of the GENETICS Perspective propose, in part because there is such an unmet need for functional annotation of the human genome.

The results of this study demonstrate a large, unmet need for attention to the sexual concerns of women who survive gynecologic and breast cancers.

With survival rates that haven't changed significantly for decades, cancers of the brain, lung, oesophagus and pancreas are notoriously difficult to treat and remain diseases of substantial unmet need.

The Company's transformative gene repair technology presents a promising opportunity to create novel therapies that address the significant unmet need in the treatment of serious genetic neuromuscular diseases.

«By this action the FDA recognizes the high unmet need for effective treatment options for patients suffering from SMA.»

Here, we address that unmet need for cell therapy biomanufacturing, in part by leveraging existing decision - engineering frameworks for biopharmaceuticals to build on the nascent body of published work geared towards cell therapies.

«At C - Path, we work collaboratively to identify mechanisms to address areas of unmet need.

«The women in the Network, like this consortium, understand that if we do not address the unmet need for family planning, the other global health goals of improving maternal, infant, and child deaths and combating infectious disease, will be difficult to achieve by 2015,» concluded Duff Gillespie, PhD, professor with the Bloomberg School's Department of Population, Family and Reproductive Health.

A substantial unmet need remains for new successful therapies in patients with this disease.

The extra financial support CRUK has given to cancers of unmet need is paying dividends — more and more researchers are clearly turning their attention to this underexplored area.

One of the cornerstones of our Research Strategy is to build capacity in research into cancers of unmet need: those we've identified due to their poor five - year survival and limited improvements in treatment in the past decade.

We may need to work together to ensure it's made clear to the decision - makers what the unmet need is in HD - but that's a problem for when we know whether the drug actually works to slow progression.

There is an unmet need to monitor human and natural environments for substances that are intentionally or unintentionally introduced.

For CRUK, cancers of unmet need are those with poor five - year survival rates, and limited improvements in treatment in the past decade.

The overarching goal of the Professional Development Core (PDC) is to address the unmet need for more diversity in the biomedical research workforce by creating and nationally disseminating transformative, high - impact, professional development programs to support mentees from diverse backgrounds in biomedical / bio-behavioral disciplines.

As Minikel explained on CureFFI.org, the registry represents an effort by a coalition of prion disease advocacy groups — the CJD Foundation, the CJD International Support Alliance, and the Prion Alliance — to fill an unmet need: a centralized way for those who want to participate in prion disease research to make their voices heard, and in the process, support clinical research on these conditions:

«This collaboration has high potential to open new avenues towards effective therapies for neurodegenerative diseases,» said Gladstone President R. Sanders Williams, MD. «Both organizations are committed to meeting this major unmet need.»

Currently, the medical management of these complications is a major unmet need for this patient population.

Importantly, NP2D will tackle not only the unmet need of new therapeutics for infectious disease, inflammation, allergy and pain, but also create a hub for interdisciplinary training for the future generation of scientists.

Thus, the identification of reliable and noninvasive biomarkers for predicting ICB responsiveness is an urgent unmet need.

«This is an unmet need for the nation's biodefense program,» said Anup Singh, senior manager for Sandia's biological science and technology group.

The U.S. Food and Drug Administration, Gladwin says, has already promised an expedited review of the treatment given that CO poisoning is a «serious unmet need.»

«One unmet need in regenerative medicine is how to effectively and safely mobilize and guide stem cells to migrate to lesion sites for repair,» Zhao said.

«We estimate that approximately four million US adults over the age of 65 suffer daily from nocturnal leg cramps, a condition for which there is significant unmet need since there are no approved treatments,» said study author Rod MacKinnon, MD, Nobel laureate and co-founder of Flex Pharma in Boston.

«It's the unmet need of asthma,» Dr. Wenzel said.

While the authors argue that legislative and contextual interventions can be effective prevention strategies, they also recognize that there is an unmet need for behavioral change programs designed to pinpoint the most at - risk groups, identify their risk and protective factors, and then design effective interventions tailored to their specific needs.

«Our new pharmacogenetic approach fills an important and unmet need in our ability to understand fly behaviors by allowing us for the first time to conveniently examine behaviors in only partially activated neurons to uncover more subtle roles for particular neurons and circuits in behaviors.»

The technique has the potential to benefit a large population of patients with neurodegenerative disorders, where there remains a specific unmet need for blood - brain penetrating therapeutic delivery strategies.

«We had focused on an unmet need, something that actually looked commercially supportable.»

These symptoms can develop as part of their condition, but may also be caused by other factors — pain, discomfort, or unmet need.

However, the different virus genotypes coupled with the complexity of the disease means there is still a major unmet need to improve options for all populations.»

Adjusted percentages of adults receiving HUD housing assistance who are uninsured, who do not have a usual source of care, and who have unmet need due to cost.

«But based on our findings, we think it could fill an unmet need in making the most common treatment for prostate cancer more effective.»