There is little chance of eliminating all carriers from a breeding program since they are not apparent «
until affected offspring are produced.
Not exact matches
However, if an X-linked disease does not arise
until an animal is breeding age, even
affected males may produce
offspring before the disease is identified.
Roughly the same situation occurs with a dominant disease that has a post - reproductive age of onset, since as many as half of the
offspring of an
affected dog will become afflicted in their lifetime, but not
until they have passed on the disease gene to half of their
offspring.