Treatment continued
until disease
progression, development of intolerance, injectable
tumor disappearance (T - VEC only), or 2 years.
When male SCID / NOD mice were injected with 5 × 106 cells, a baseline signal was not reported
until two weeks after inoculation (Mitsiades et al., 2004), while Azab and colleagues, which inoculated 2 × 106 MM.1S - luc cells, reported that it took 3 — 4 weeks for sufficient
tumor progression to occur and be detected (Azab et al., 2009).