In cases where a brain tumor begins growing autonomously in the brain, mutations, in the DNA of brain cells cause the cells to grow and divide, forming a mass that is made
up of abnormal cells.
Not exact matches
«What our findings show is that the problems with iPS
cells don't just involve one or two or a few
abnormal iPS
cells escaping into the body and forming tumors, but that the whole population
of cells is screwed
up,» Lanza says.
At worst we would end
up with a few little pebble tumors, small balls
of abnormal cells that had exhausted their ability to grow, no more life - threatening than a mole or a small cyst.
Several
of the proteins characteristic
of cancer
cells seem to show
up in these nerve
cells, and this is very
abnormal.
This turned out to be a normal protein in the
cells of organisms throughout the animal kingdom — but in brains infected with scrapie and related diseases it turns
up in both a normal, soluble form and an
abnormal, insoluble form which accumulates in deposits that eventually kill the
cells.
In
cells from sick hearts, these channels often don't inactivate properly, allowing for excess sodium entry and a build -
up of calcium, which ultimately promotes
abnormal heart rate (arrhythmia) and symptoms
of heart failure.
Key findings
of this research, which was conducted by Shawn L. Chavez, PhD and her colleagues at Stanford University and analyzed at OHSU, showed that by looking at the duration
of the first mitotic phase — a short period in the
cell cycle — one can identify chromosomally normal versus
abnormal embryos
up to approximately the 8 -
cell stage.
• Keeping
abnormal proteins from building
up and potentially shutting down major organs (heart, liver and nervous system, to name a few) • Protecting the brain's functions
of learning and memory against neurotransmitter toxicity • Activating or increasing the activity
of proteins that promote the initial growth, maintenance and survival
of brain neurons • Enhancing the movement
of proteins, lipids and other
cell parts through the cytoplasm
of cell bodies.
«By comparing these diseased neurons with the «genetically corrected» healthy neurons, we could see —
cell by
cell — how the Tau mutation leads to the
abnormal build
up of Tau and, over time, neuronal degeneration and death.»
In this type
of plasma
cell neoplasm, less than 10 %
of the bone marrow is made
up of abnormal plasma
cells and there is no cancer.
Multiple myeloma
cells are
abnormal plasma
cells (a type
of white blood
cell) that build
up in the bone marrow and form tumors in many bones
of the body.
Deep inside the brains
of people with dementia and Lou Gehrig's disease, globs
of abnormal protein gum
up the inner workings
of brain
cells — dooming them to an early death.
The reason this process goes un-noticed and is inconsequential the overwhelming majority
of the time, is because our immune systems are
up to the task
of identifying and clearing the
abnormal cells before they have a chance to gain an established presence and / or spread in our bodies.