Sentences with phrase «up of adenosine»

Researchers think that this build - up of adenosine during wakefulness may promote the drive to sleep.

Not exact matches

For this reason, Salvemini and colleagues teamed up with researchers from the National Institutes of Health, the University of Arizona and two institutes in Quebec, Canada, to investigate a new target for treating chronic pain: the A3 adenosine receptor or A3AR.

Cronstein and his team also found that levels of adenosine A2A receptors went up on rat chondrocytes when osteoarthritis was present, in what the researchers say was a «failed attempt» to compensate for the loss of adenosine from the energy - processing (metabolic) changes underlying the inflammation.

In tissues such as liver and skeletal muscle, FAO can provide over 75 % of cellular adenosine triphosphate, while in cardiac tissue it can be responsible for up to 90 %.

Methotrexate enhances the anti-inflammatory effect of CF101 via up - regulation of the A3 adenosine receptor expression.

DNA is made up of only 4 different genetic building blocks called nucleotides, which are named cytosine ©, guanine (G), adenosine (A) and thymidine (T).

8.30 Hana Paculová CDK12 connects transcriptional regulation to DNA damage repair pathway 8.55 Karol Kaiser Wnt secretion during nervous system development 9.20 Simona Hankeová The role of Notch signaling in vasculogenesis 10.00 Coffee break 10.30 Tomáš Doležal Extracellular adenosine regulates complex host - pathogen interactions through the energy release for the immune response 10.55 Ondřej Bernatík and Igor Červenka Regulation of diverse function of Dvl by phosphorylation 11.20 Jan Ryneš Dissection of Axin interactome: rational approach for control of signaling cascades via intervention with specific protein - protein interactions 12.05 Targeting opportunities: discussion & sum - up 13.00 Lunch and departure

When endurance athletes train, they use up the glycogen in their muscles, but when bodybuilders train they use adenosine triphosphate (ATP) which is a whole other fuel source and also a major source of energy for most cellular functions in a human body.

By sleeping for 20 of those 30 minutes, the amount of adenosine the caffeine competes with is reduced, so the stimulant provides a bit of a boost right when you wake up.

While you're busy catching up on zzz's, though, your body clears itself of adenosine, which allows you to awaken feeling alert and refreshed, rather than tired.

In order for this required ATP energy to continue the Creatine phosphate is able to give up one of its phosphate molecules to form ADP (adenosine - diphosphate).

One of the reasons we feel refreshed and alert when we wake up is that while we're awake, neurons in the brain produce adenosine, a by - product of the cells» activities.

This explains why regular coffee drinkers build up a tolerance over time — because you have more adenosine receptors, it takes more caffeine to block a significant proportion of them and achieve the desired effect.

Another factor that supports our sleep - wake cycle is the build - up of a sleep chemical called adenosine.

And, as a result, when we wake up in the morning, the levels of adenosine — and sleepiness — are lowest and we feel refreshed.