Sentences with phrase «upon oncogenic»
Jeffrey A. Toretsky, M.D. Georgetown University Novel cancer therapeutics based upon oncogenic fusion - protein transcription factors
https://www.bwfund.org/
Molecular characterization of the cells that undergo cell fate transition upon oncogenic Pik3ca expression demonstrated a profound oncogene - induced reprogramming of these newly formed cells and identified gene expression signatures, characteristic of the different cell fate switches, which was predictive of the cancer cell of origin, tumour type and clinical outcomes in women with breast cancers.