Although B16F10 cells are without mutations in Braf, Kras or Nras, it is highly possible that mutations in Pdgfra (well known to activate ERK1 / 2) as well as Atm (well known to activate PI3K - AKT) are responsible for the constitutive expression of ERK1 / 2 and AKT in B16F10 cells [24],
upon radiation exposure.
Not exact matches
Phosphorylated ERK1 / 2 and p - AKT were increased in a dose - dependent manner
upon exposure to 1.0, 2.0 and 3.0 Gy of
radiation at 4 h of post-irradiation (P < 0.01 to 0.0001).
Actually a hormone, not a vitamin, vitamin D is produced in the skin
upon exposure to UV
radiation from the sun.
Extensive research into the impact this flood of technology is having
upon us is providing solid evidence that chronic
exposure to even low - level
radiation (like that from mobile / cell phones), can cause a variety of cancers (especially brain cancer), impair immunity, and contribute to Alzheimer's disease, dementia, heart disease, and many other ailments.
Although cats continue to secrete the radioisotope for several weeks
upon their return home, the resulting
radiation exposure to the owner is less than the
radiation experienced by a passenger on a round - trip flight from New York to Los Angeles.