Sentences with phrase «upper urinary tract»

For years, scientists have known of some mutations in upper urinary tract cancer patients exposed to the plant toxin.

In comparison with former times, this indicates a markedly decreased incidence of upper urinary tract infections.

To get a broader picture, Teh and colleagues sequenced tissue from nine Taiwanese patients with upper urinary tract cancer who had taken birthwort.

«Scientists use genome sequencing to demonstrate herbal remedy causes upper urinary tract cancers.»

Because upper urinary tract cancer manifests itself in the kidneys, the researchers used the latest genetic sequencing methods to examine cancerous kidney tissue side by side with nearby nontumorous tissue.

For the current study, the Johns Hopkins and Stony Brook team used whole - exome sequencing on 19 Taiwanese upper urinary tract cancer patients exposed to aristolochic acid, and seven patients with no suspected exposure to the toxin.

«I thought there should be more than that,» says Teh, who has long been struck by the fact that Taiwan, with high use of supplements containing birthwort, also has the highest known incidence of upper urinary tract cancer in the world.

Genomic sequencing experts at Johns Hopkins partnered with pharmacologists at Stony Brook University to reveal a striking mutational signature of upper urinary tract cancers caused by aristolochic acid, a plant compound contained in herbal remedies used for thousands of years to treat a variety of ailments such as arthritis, gout and inflammation.

In fact, «kidney infections are still technically UTIs, since kidneys are part of your upper urinary tract,» according to the National Institute of Diabetes and Digestive and Kidney Diseases.

And although a few studies had shown a link between birthwort and either upper urinary tract cancer or kidney disease, they had only traced the mechanism as far as mutations on one gene: P53, a gene commonly associated with cancer.

After sequencing tissue taken from 19 Taiwanese patients with upper urinary tract cancer, the researchers found that a control group of patients with upper urinary tract cancer but no history of birthwort use did not show the same pattern of mutations.

Stone formation in the upper urinary tract often leads to inflammation in the urinary tract.

They can be a sign of a more serious infection of the urinary tract, though they are usually not difficult to treat Some UTIs affect the lower tract and others affect the upper urinary tract.

This form of lithtripsy is used to fragment stones in the upper urinary tract: the kidney and ureter.

Another disadvantage of cystoscopy is that it does not evaluate the upper urinary tract so usually some other form of imaging is needed to complement cystoscopy.

Kidney stones in dogs (nephroliths) generally do not cause significant disease but, in some circumstances, they can lead to pyelonephritis (a bacterial infection of the dog's upper urinary tract and kidney) and chronic renal failure in dogs.

Your veterinarian will try and determine if the problem is in the lower or upper urinary tract.

This involves directly inserting a needle into the urinary bladder; the advantage of this procedure is that the sample collected does not contact the lower urinary tract and genitalia, so thus is sterile and representative of the upper urinary tract (kidneys, ureters and bladder).

Infection can be found in either the upper urinary tract, lower urinary tract or both.