Sentences with phrase «upper urinary tract cancer»

After sequencing tissue taken from 19 Taiwanese patients with upper urinary tract cancer, the researchers found that a control group of patients with upper urinary tract cancer but no history of birthwort use did not show the same pattern of mutations.

And although a few studies had shown a link between birthwort and either upper urinary tract cancer or kidney disease, they had only traced the mechanism as far as mutations on one gene: P53, a gene commonly associated with cancer.

«I thought there should be more than that,» says Teh, who has long been struck by the fact that Taiwan, with high use of supplements containing birthwort, also has the highest known incidence of upper urinary tract cancer in the world.

To get a broader picture, Teh and colleagues sequenced tissue from nine Taiwanese patients with upper urinary tract cancer who had taken birthwort.

Because upper urinary tract cancer manifests itself in the kidneys, the researchers used the latest genetic sequencing methods to examine cancerous kidney tissue side by side with nearby nontumorous tissue.

Genomic sequencing experts at Johns Hopkins partnered with pharmacologists at Stony Brook University to reveal a striking mutational signature of upper urinary tract cancers caused by aristolochic acid, a plant compound contained in herbal remedies used for thousands of years to treat a variety of ailments such as arthritis, gout and inflammation.

«Scientists use genome sequencing to demonstrate herbal remedy causes upper urinary tract cancers.»

Not exact matches

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