Sentences with phrase «upstream regions with»

Not exact matches

This SNP is also within a region associated with body size in this study (near HMGA2), although the strongest signal for ear position occurs nearly 0.5 Mb upstream, near MSRB3 (Figure S3).

In contrast to the preferred upstream regions associated with peak KD events, the high - residence time regions associated with low KD incidence appear to lie mostly in the sea between China and Japan (Fig. 3B).

We sought to define this upstream methylation boundary and investigate whether Wilms» tumors with loss of imprinting are biallelically methylated in this upstream region.

Wilms» tumors with loss of imprinting showed varying degrees of biallelic methylation in the H19 upstream repeat region also affecting one of the 42 bp elements which leads us to suggest that pathological methylation in this region may be the epigenetic error that initiates H19 silencing.

Conserved regions include the IR1 latency promoter (Wp), and one zone upstream of and two within BWRF1.IR1 is heterogeneous in 70 % of strains, and this heterogeneity arises from sequence exchange between strains as well as spontaneous mutation, with inter-strain recombination more common in tumour - derived viruses.

Derivatives of this basic construct included removal of the alternative exon 4 by deleting an Nhe I / Apa I fragment (nucleotides 12,259 — 12,543; Figure 3D); replacement of the genomic region covering exons 2 — 6 with the corresponding cDNA sequence (Sal I to Nco I; nucleotides 14,412 — 11,736; Figure 3E) plus additional upstream sequence to allow for recombination with F56B12 (to the Xho I site at nucleotide 15,574); and introduction of a Met to Leu mutation (M121L, ATG to CTG) by PCR amplification with primers that included the sequence change (nucleotides 11,968 — 11,970; Figure 3F).

The latest BBM Beta brought it with it several new features including the all new BBM Sticker Club, BlackBerry OS 10.3.2.2639 began rolling out to multiple regions and devices, John Chen will be speaking at Code / Mobile in October, and there was a another edition of the BerryFlow Upstream Podcast.

Their observations were that the region of lightly grounded ice at the glacier terminus is extending upstream, and the changes inland are consistent with the effects of a prolonged disturbance to the ice flow, such as the effects of ocean - driven melting.

Allelic variation in this transporter's gene expression, regulated by a 43 bp indel in the upstream region termed 5 - HTTLPR, was initially associated with anxiety - related traits (23) and has since been investigated in many fields of serotonin - related human genetics (24).