Sentences with phrase «urea cycle»

Recently, a young girl who suffers from a rare disease called urea cycle disorder visited Horizon's offices.

The lack of down - regulatory control over aminotransferases and urea cycle enzymes renders cats immediately able to metabolize and use amino acids for gluconeogenesis and as an energy source.

A medication that blocks ER stress is already on the market to treat an entirely different condition called urea cycle disorder.

Cats have an inability to downregulate protein degradation and need arginine to dispose of the nitrogens via urea cycle.

CZARNECKI, G.L.; BAKER, D.H. Urea cycle function in the dog with emphasis on the role of arginine.

In the area of metabolic disease, he has studied nitric oxide dysregulation and developed new treatments for maple syrup urine disease and urea cycle disorders.

This appears to be because cats have a limited ability to control the activity of their aminotransferases and urea cycle enzymes (Rogers et al., 1977; Green et al., 2008).

WND 2 is an iron - fortified medical food powder that is free of nonessential amino acids for children and adults with inborn errors of the urea cycle (waste nitrogen disorders).

The alterations in these metabolites, which include key components of the urea cycle and nitric oxide pathways (both vital body processes), suggest that both of these processes are dysregulated in the early stages of Huntington's disease, and that the illness affects the body long before physical symptoms appear.

Additionally, enhanced hiPS - HEP cells express genes involved in the urea cycle within the same range as hphep cells (Figure 3, Panel D), and the cells secrete albumin and urea (Figure 3, Panels E and F).

Additionally, the enhanced hiPS - HEP cells express genes involved in the urea cycle within the same range as hphep cells, and the cells secrete albumin and urea.

Nakagawa T, Lomb DJ, Haigis MC, Guarente L. SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle.

Since then, he has made important genetic, mechanistic, and clinical discoveries related to skeletal dysplasias and urea cycle disorders, translated these discoveries into therapeutic advances, and tested these therapies in clinical trials.

Arginine plays a pivotal role in the urea cycle, helping to rid the body of excess ammonia.

The ammonia is combined with carbon dioxide in the urea cycle, and excreted in urine, and the carbon skeleton can be either used for energy directly or converted into other compounds, such as glucose or fatty acids.

This amino acid is transitional in the urea cycle.

During fasting / starvation your body tries to downregulate the urea cycle because you can't really afford to be «wasting» amino acids / protein.

Ornithine is a non-essential amino acid that plays a central role in the urea cycle, functioning along with Arginine and Citrulline to rid the body of ammonia, a byproduct of protein metabolism.

Citrulline - an amino acid that is involved in the urea cycle and is a precursor along with arginine for nitric oxide *.

Ornithine - an amino acid that is involved in the urea cycle and is a precursor of arginine.

L - arginine is important in the urea cycle for the metabolism of ammonia produced in the breakdown of protein.

L - arginine is considered a semi-essential amino acid, and is involved in growth hormone release, the production of nitric oxide, and the metabolism of ammonia waste in the urea cycle.

Ammonia is toxic to the body, so enzymes convert it to urea by addition of carbon dioxide in the urea cycle, which takes place in the liver.

The moderately high and fixed activity of the urea cycle provides a safeguard against ammonia toxicity after ingestion of a high - protein meal.