Sentences with word «uridine»

Polysaccharides and glycans are made by the sequential addition of monosaccharides by glycosyltransferase from a reactive sugar - phosphate donor such as uridine diphosphate glucose (UDP - glucose) to an acceptor hydroxyl group on the growing polysaccharide.
Similarly, rats injected with high levels of uridine were equally tenacious.
All of the cells were allowed to attach for 4 hr before the elongation - device chamber was filled with complete medium containing the mitotic inhibitors [mitotic inhibitor 1 (MI1), 5 μm cytosine β - d - arabinofuranoside (AraC; Sigma, St. Louis, MO), 20 μm 5 - fluoro - 2 ′ - deoxyuridine (5FdU; Sigma), and 20 μm uridine (Sigma)-RSB-.
A team of researchers led by neurobiologist William Carlezon at Harvard's McLean Hospital in Belmont, Massachusetts, studied how omega - 3 fatty acids and uridine affect the behavior of rats using a standard depression test.
In addition to the control chow, some of the APP / PS1 mice were fed three experimental chows enriched with fish oil and having a similar fat content as the control chow: fish oil supplement only, plant sterol supplement or Fortasyn supplement, which contains uridine - monophosphate, phospholipids, B - vitamins, and antioxidants.
Platelet - associated galactosyltransferase produces efficient galactosylation when uridine diphosphate — galactose is added, affording a potentially simple method for storing platelets in the cold.
Other studies suggest that the nutrient uridine also affects brain function.
The team now hopes to formulate a new uridine - based antidepressant treatment for humans.
And uridine fuels chemical reactions in mitochondria and may boost the cellular communications that control mood and other mental processes.
Particular cytidines in transcripts in chloroplasts and mitochondria of plant cells undergo modification to uridine by RNA editing (1).
The probe we used in the in situ hybridizations was ribosomal RNA labeled with tritiated uridine, and we used Xenopus rRNA because it was available from tissue culture cells.
Nucleotides: cytidine 5» - monophosphate, disodium guanosine 5» - monophosphate, disodium uridine 5» - monophosphate, adenosine 5» - monophosphate; 10.
After 2 d, the medium was exchanged with complete medium plus the mitotic inhibitors (MI2, 20 μm 5FdU, and 20 μm uridine) for 3 d. Thereafter, the medium was changed every 2 - 3 d, and MI2 was reapplied once a week.
And early research finds that another important nutrient found in beets — uridine — is as effective as prescription antidepressants when it's combined with omega - 3s.
Cytidines or uridines are added to C5 to generate chain lengths of 10 to 11 nucleotides, with longer products being generated at greatly reduced efficiency.
But she and her UPenn colleague Drew Weissman found a way to tame cells» typical inflammatory response by modifying one of mRNA's four building blocks, uridine.
This cellular machinery translates its sequence of four kinds of nucleosides — adenosine, cytidine, uridine, and guanosine — into a protein.
Examples include cytidine, uridine, adenosine, guanosine, thymidine and inosine.
Liu and coworkers developed last year's base editor by combining three proteins: a cytidine deaminase, a natural enzyme that converts C to uridine (U); a mutated Cas9 CRISPR enzyme that doesn't cut DNA but uses an associated guide RNA to target specific DNA sequences; and a protein that prevents reversion of U back to C.
Unfortunately, the uridine found in food is not bioavailable, and no food has been shown to increase levels of uridine in the brain (22).
The formation of synapses depends on sufficient brain levels of three key nutrients — uridine, omega - 3 fatty acids, and choline.
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